Browsing by Author "Sarracino, David A."
Now showing items 1-4 of 4
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Comparative Proteomic Analysis of the PhoP Regulon in Salmonella enterica Serovar Typhi Versus Typhimurium
Lebrun, Lauren M.; Sheikh, Alaullah; Logvinenko, Tanya; Tarique, Abdullah; Krastins, Bryan; Qadri, Firdausi; Charles, Richelle Candice; Harris, Jason B.; Chase, Michael Richard; Larocque, Regina Celes; Rollins, Sean McKenzie; Hohmann, Elizabeth Louise; Rosenberg, Ian Morley; Sarracino, David A.; Calderwood, Stephen Beaven; Ryan, Edward Thomas (Public Library of Science, 2009)Background: S. Typhi, a human-restricted Salmonella enterica serovar, causes a systemic intracellular infection in humans (typhoid fever). In comparison, S. Typhimurium causes gastroenteritis in humans, but causes a systemic ... -
EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity
Garces, Alejandra; Woodworth, Joshua S.; Krastins, Bryan; Atmakuri, Krishnamohan; Chase, Michael Richard; Rothchild, Alissa C.; Ramsdell, Talia Lynn; Lopez, Mary Frances; Behar, Samuel M; Sarracino, David A.; Fortune, Sarah Merritt (Public Library of Science, 2010)Mycobacterium tuberculosis (Mtb) requires the ESX1 specialized protein secretion system for virulence, for triggering cytosolic immune surveillance pathways, and for priming an optimal CD8+ T cell response. This suggests ... -
The Genome and Structural Proteome of an Ocean Siphovirus: A New Window into the Cyanobacterial ‘Mobilome’
Sullivan, Matthew; Krastins, Bryan; Hughes, Jennifer L; Kelly, Libusha; Chase, Michael Richard; Sarracino, David A.; Chisholm, Sallie W (Blackwell Publishing, 2009)Prochlorococcus, an abundant phototroph in the oceans, are infected by members of three families of viruses: myo-, podo- and siphoviruses. Genomes of myo- and podoviruses isolated on Prochlorococcus contain DNA replication ... -
Proteins other than the locus of enterocyte effacement-encoded proteins contribute to Escherichia coli O157:H7 adherence to bovine rectoanal junction stratified squamous epithelial cells
Kudva, Indira T; Griffin, Robert; Krastins, Bryan; Sarracino, David A.; Calderwood, Stephen Beaven; John, Manohar (BioMed Central, 2012)Background: In this study, we present evidence that proteins encoded by the Locus of Enterocyte Effacement (LEE), considered critical for Escherichia coli O157 (O157) adherence to follicle-associated epithelial (FAE) cells ...