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    • Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo 

      Maldini, Colby R.; Claiborne, Daniel T.; Okawa, Ken; Chen, Tao; Dopkin, Derrick L.; Shan, Xiaochuan; Power, Karen A.; Trifonova, Radiana T.; Krupp, Katharine; Phelps, Meredith; Vrbanac, Vladimir D.; Tanno, Serah; Bateson, Timothy; Leslie, George J.; Hoxie, James A.; Boutwell, Christian L; Riley, James L.; Allen, Todd M. (Springer Science and Business Media LLC, 2020-08-31)
      A potent and sustained antiviral T cell response will likely be a critical component of an effective HIV cure strategy. Here, we explored the utility of CD4-based Chimeric Antigen Receptor (CAR) T cells to mitigate HIV-induced ...