Browsing by Author "Massarotti, Elena"
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Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals
Mercer, Emileigh; Rekedal, Laura; Garg, Rajesh Kumar; Lu, Bing; Massarotti, Elena M.; Solomon, Daniel Hal (BioMed Central, 2012)Introduction: Hydroxychloroquine (HCQ) is a common disease modifying therapy for the treatment of rheumatoid arthritis (RA). Prior research suggests that HCQ may reduce the risk of diabetes mellitus in patients with RA. ... -
Pathologically Expanded Peripheral T Helper Cell Subset Drives B Cells in Rheumatoid Arthritis
Rao, Deepak; Gurish, Michael F.; Marshall, Jennifer L.; Slowikowski, Kamil; Fonseka, Chamith Y.; Liu, Yanyan; Donlin, Laura T.; Henderson, Lauren; Wei, Kevin; Mizoguchi, Fumitaka; Teslovich, Nikola; Weinblatt, Michael; Massarotti, Elena; Coblyn, Jonathan; Helfgott, Simon; Lee, Yvonne C.; Todd, Derrick; Bykerk, Vivian P.; Goodman, Susan M.; Pernis, Alessandra B.; Ivashkiv, Lionel B.; Karlson, Elizabeth; Nigrovic, Peter; Filer, Andrew; Buckley, Christopher D.; Lederer, James; Raychaudhuri, Soumya; Brenner, Michael (Springer Science and Business Media LLC, 2017-02-02)CD4+ T cells are central mediators of autoimmune pathology; however, defining their key effector functions in specific autoimmune diseases remains challenging. Pathogenic CD4+ T cells within affected tissues may be identified ... -
The potential role of 'non-rheumatic’ therapies in rheumatic disease
Massarotti, Elena M; Solomon, Daniel H (BioMed Central, 2013)The relationship between inflammation and insulin resistance is complex and not fully understood. Patients with rheumatoid arthritis are at increased risk of mortality from cardiovascular disease, which is known to be ...