Browsing by Author "Milton, Donald"
Now showing items 1-18 of 18
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Airborne Rhinovirus Detection and Effect of Ultraviolet Irradiation on Detection by a Semi-Nested RT-PCR Assay
Myatt, Theodore A; Johnston, Sebastian L; Rudnick, Stephen N.; Milton, Donald Kirby (BioMed Central, 2003)Background: Rhinovirus, the most common cause of upper respiratory tract infections, has been implicated in asthma exacerbations and possibly asthma deaths. Although the method of transmission of rhinoviruses is disputed, ... -
Characterization of Occupational Exposures to Cleaning Products Used for Common Cleaning Tasks-A Pilot Study of Hospital Cleaners
Bello, Anila; Quinn, Margaret M.; Perry, Melissa J.; Milton, Donald Kirby (BioMed Central, 2009)Background: In recent years, cleaning has been identified as an occupational risk because of an increased incidence of reported respiratory effects, such as asthma and asthma-like symptoms among cleaning workers. Due to ... -
Collection of Aerosolized Human Cytokines Using Teflon® Filters
McKenzie, Jennifer Helen; McDevitt, James J; Fabian, Maria Patricia; Hwang, Grace M.; Milton, Donald Kirby (Public Library of Science, 2012)Background: Collection of exhaled breath samples for the analysis of inflammatory biomarkers is an important area of research aimed at improving our ability to diagnose, treat and understand the mechanisms of chronic ... -
Effects of Endotoxin Exposure on Childhood Asthma Risk are Modified by a Genetic Polymorphism in ACAA1
Sordillo, Joanne; Sharma, Sunita; Poon, Audrey; Su, Jessica Ann Lasky; Belanger, Kathleen; Milton, Donald Kirby; Bracken, Michael B; Triche, Elizabeth W; Leaderer, Brian P; Gold, Diane R.; Litonjua, Augusto Ampil (BioMed Central, 2011)Background: Polymorphisms in the endotoxin-mediated TLR4 pathway genes have been associated with asthma and atopy. We aimed to examine how genetic polymorphisms in innate immunity pathways interact with endotoxin to influence ... -
Home endotoxin exposure and wheeze in infants: correction for bias due to exposure measurement error
Horick, Nora; Weller, Edie A.; Milton, Donald Kirby; Gold, Diane R.; Li, Ruifeng; Spiegelman, Donna Lynn (National Institute of Environmental Health Sciences, 2005)Exposure to elevated levels of endotoxin in family-room dust was previously observed to be significantly associated with increased wheeze in the first year of life among a cohort of 404 children in the Boston, Massachusetts, ... -
Hypersensitivity Pneumonitis Associated with Environmental Mycobacteria
Beckett, William Stewart; Kallay, Michael; Sood, Akshay; Zuo, Zhengfa; Milton, Donald Kirby (National Institue of Environmental Health Sciences, 2005)A previously healthy man working as a machine operator in an automotive factory developed respiratory symptoms. Medical evaluation showed abnormal pulmonary function tests, a lung biopsy showed hypersensitivity pneumonitis, ... -
Inactivation of Poxviruses by Upper-Room UVC Light in a Simulated Hospital Room Environment
McDevitt, James J; Milton, Donald Kirby; Rudnick, Stephen N.; First, Melvin W. (Public Library of Science, 2008)In the event of a smallpox outbreak due to bioterrorism, delays in vaccination programs may lead to significant secondary transmission. In the early phases of such an outbreak, transmission of smallpox will take place ... -
Influenza and Ultraviolet Germicidal Irradiation
Radonovich, Lewis J.; Martinello, Richard A.; Hodgson, Michael; Milton, Donald Kirby; Nardell, Edward Anthony (BioMed Central, 2008) -
Influenza Virus Aerosols in Human Exhaled Breath: Particle Size, Culturability, and Effect of Surgical Masks
Milton, Donald Kirby; Fabian, Maria Patricia; Cowling, Benjamin J.; Grantham, Michael L.; McDevitt, James J (Public Library of Science, 2013)The CDC recommends that healthcare settings provide influenza patients with facemasks as a means of reducing transmission to staff and other patients, and a recent report suggested that surgical masks can capture influenza ... -
Influenza Virus in Human Exhaled Breath: An Observational Study
Fabian, Patricia; McDevitt, James J; DeHaan, Wesley H.; Fung, Rita O. P.; Cowling, Benjamin J.; Chan, Kwok Hung; Leung, Gabriel M.; Milton, Donald Kirby; Fouchier, Ron A. M. (Public Library of Science, 2008)Background: Recent studies suggest that humans exhale fine particles during tidal breathing but little is known of their composition, particularly during infection. Methodology/Principal Findings: We conducted a study of ... -
A Longitudinal Study of Adult-Onset Asthma Incidence among HMO Members
Sama, Susan R; Hunt, Phillip R; Cirillo, CIH Priscilla; Marx, Arminda; Rosiello, Richard A; Henneberger, Paul K; Milton, Donald Kirby (BioMed Central, 2003)Background: HMO databases offer an opportunity for community based epidemiologic studies of asthma incidence, etiology and treatment. The incidence of asthma in HMO populations and the utility of HMO data, including use ... -
Occupational Asthma and Contact Dermatitis in a Spray Painter after Introduction of an Aziridine Cross-Linker.
Leffler, C T; Milton, Donald Kirby (The National Institute of Environmental Health Sciences, 1999)A 23-year-old spray painter developed contact dermatitis and respiratory difficulty characterized by small airways obstruction shortly after the polyfunctional aziridine cross-linker CX-100 began to be used in his workplace ... -
Populations and determinants of airborne fungi in large office buildings
Chao, H Jasmine; Schwartz, Joel David; Milton, Donald Kirby; Burge, Harriet A (National Institute of Environmental Health Sciences, 2002)Bioaerosol concentrations in office environments and their roles in causing building-related symptoms have drawn much attention in recent years. Most bioaerosol studies have been cross-sectional. We conducted a longitudinal ... -
Prevalence of asthma and allergies in children from the Greek-Cypriot and Turkish-Cypriot communities in Cyprus: a bi-communal cross-sectional study
Lamnisos, Demetris; Moustaki, Maria; Kolokotroni, Ourania; Koksoy, Huseyin; Faiz, Muharrem; Arifoglu, Kenan; Milton, Donald K; Middleton, Nicos; Yiallouros, Panayiotis K (BioMed Central, 2013)Background: The Greek-Cypriot (G/C) and Turkish-Cypriot (T/C) communities have lived apart since 1974, with the former presumably adopting a more westernized way of life. We estimated the prevalence of asthma and allergies ... -
Quantitative Assessment of Airborne Exposures Generated during Common Cleaning Tasks: A Pilot Study
Bello, Anila; Quinn, Margaret M.; Perry, Melissa J.; Milton, Donald Kirby (BioMed Central, 2010)Background: A growing body of epidemiologic evidence suggests an association between exposure to cleaning products with asthma and other respiratory disorders. Thus far, these studies have conducted only limited quantitative ... -
A Study of Indoor Carbon Dioxide Levels and Sick Leave among Office Workers
Myatt, Theodore A; Staudenmayer, John; Adams, Kate; Walters, Michael D.; Rudnick, Stephen N.; Milton, Donald Kirby (BioMed Central, 2002)Background: A previous observational study detected a strong positive relationship between sick leave absences and carbon dioxide (CO2) concentrations in office buildings in the Boston area. The authors speculated that the ... -
What was the primary mode of smallpox transmission? Implications for biodefense
Milton, Donald Kirby (Frontiers Media S.A., 2012)The mode of infection transmission has profound implications for effective containment by public health interventions. The mode of smallpox transmission was never conclusively established. Although, “respiratory droplet” ... -
Within-home versus between-home variability of house dust endotoxin in a birth cohort
Abraham, Joseph H.; Gold, Diane R.; Dockery, Douglas W.; Ryan, Louise Marie; Park, Ju-Hyeong; Milton, Donald Kirby (National Institute of Environmental Health Sciences, 2005)Endotoxin exposure has been proposed as an environmental determinant of allergen responses in children. To better understand the implications of using a single measurement of house dust endotoxin to characterize exposure ...