Browsing by Author "VanderWeele, Tyler"
Now showing items 1-16 of 16
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An Assessment of Health Behavior Peer Effects in Peking University Dormitories: A Randomized Cluster-Assignment Design for Interference
Yuan, Changzheng; Lv, Jun; VanderWeele, Tyler J. (Public Library of Science, 2013)Background: Relatively little is known about the peer influence in health behaviors within university dormitory rooms. Moreover, in China, the problem of unhealthy behaviors among university students has not yet been ... -
Associations between Mental Health and Ebola-Related Health Behaviors: A Regionally Representative Cross-sectional Survey in Post-conflict Sierra Leone
Betancourt, Theresa S.; Brennan, Robert T.; Vinck, Patrick; VanderWeele, Tyler J.; Spencer-Walters, Dayo; Jeong, Joshua; Akinsulure-Smith, Adeyinka M.; Pham, Phuong (Public Library of Science, 2016)Background: Little attention has been paid to potential relationships between mental health, trauma, and personal exposures to Ebola virus disease (EVD) and health behaviors in post-conflict West Africa. We tested a ... -
Birth weight and later life adherence to unhealthy lifestyles in predicting type 2 diabetes: prospective cohort study
Li, Yanping; Ley, Sylvia H; Tobias, Deirdre K; Chiuve, Stephanie E; VanderWeele, Tyler J; Rich-Edwards, Janet W; Curhan, Gary C; Willett, Walter C; Manson, JoAnn E; Hu, Frank B; Qi, Lu (BMJ Publishing Group Ltd., 2015)Objectives To prospectively assess the joint association of birth weight and established lifestyle risk factors in adulthood with incident type 2 diabetes and to quantitatively decompose the attributing effects to birth ... -
Causal Mediation Analysis With Time-Varying and Multiple Mediators
Lin, Sheng-Hsuan (2016-05-03)The assessment of direct and indirect effects with time-varying and multiple mediators is a common but challenging problem, and standard mediation analysis approaches are generally not applicable in this context. This ... -
Factors influencing the decision to participate in medical premarital examinations in Hubei Province, Mid-China
Wang, Peigang; Wang, Xiao; Fang, Min; VanderWeele, Tyler J. (BioMed Central, 2013)Background: To investigate the attitudes of premarital couples towards the premarital screening program after the abolition of compulsory screening in China and to study the factors influencing participation. Methods: ... -
The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study
Carere, Deanna Alexis; VanderWeele, Tyler; Moreno, Tanya A.; Mountain, Joanna L.; Roberts, J. Scott; Kraft, Peter; Green, Robert C. (BioMed Central, 2015)Background: Direct access to genomic information has the potential to transform cancer risk counseling. We measured the impact of direct-to-consumer genomic risk information on changes to perceived risk (ΔPR) of breast, ... -
Interaction between Arsenic Exposure from Drinking Water and Genetic Polymorphisms on Cardiovascular Disease in Bangladesh: A Prospective Case-Cohort Study
Wu, Fen; Jasmine, Farzana; Kibriya, Muhammad G.; Liu, Mengling; Cheng, Xin; Parvez, Faruque; Islam, Tariqul; Ahmed, Alauddin; Rakibuz-Zaman, Muhammad; Jiang, Jieying; Roy, Shantanu; Paul-Brutus, Rachelle; Slavkovich, Vesna; Levy, Diane; VanderWeele, Tyler J.; Pierce, Brandon L.; Graziano, Joseph H.; Ahsan, Habibul; Chen, Yu (NLM-Export, 2015)Background: Epidemiologic data on genetic susceptibility to cardiovascular effects of arsenic exposure from drinking water are limited. Objective: We investigated whether the association between well-water arsenic and ... -
Mammographic density and breast cancer risk: a mediation analysis
Rice, Megan S.; Bertrand, Kimberly A.; VanderWeele, Tyler J.; Rosner, Bernard A.; Liao, Xiaomei; Adami, Hans-Olov; Tamimi, Rulla M. (BioMed Central, 2016)Background: High mammographic density (MD) is a strong risk factor for breast cancer. However, it is unclear whether high MD is an intermediate phenotype or whether breast cancer risk factors influence breast cancer risk ... -
Mammographic density as a mediator for breast cancer risk: analytic approaches
VanderWeele, Tyler J; Adami, Hans-Olov; Tamimi, Rulla M (BioMed Central, 2012)Mammographic breast density has been found to be associated with breast cancer risk. Many of the traditional risk factors for breast cancer are themselves associated with mammographic breast density. A natural question ... -
Positive parenting improves multiple aspects of health and well-being in young adulthood
Chen, Ying; Haines, Jess; Charlton, Brittany; VanderWeele, Tyler (Springer Science and Business Media LLC, 2019-05-06)Aspects of positive parenting have previously been linked to better offspring health and well-being1,2, though often, individual outcomes have been examined separately. Examining multiple outcomes simultaneously, over ... -
A proposed clinical and biological interpretation of mediated interaction
Ikram, M. Arfan; VanderWeele, Tyler J. (Springer Netherlands, 2015)Understanding of causal pathways in epidemiology involves the concepts of direct and indirect effects. Recently, causal mediation analysis has been formalized to quantify these direct and indirect effects in the presence ... -
Quantifying the Role of Adverse Events in the Mortality Difference between First and Second-Generation Antipsychotics in Older Adults: Systematic Review and Meta-Synthesis
Jackson, John W.; Schneeweiss, Sebastian; VanderWeele, Tyler J.; Blacker, Deborah (Public Library of Science, 2014)Background: Observational studies have reported higher mortality among older adults treated with first-generation antipsychotics (FGAs) versus second-generation antipsychotics (SGAs). A few studies examined risk for medical ... -
Sensitivity Analysis for Linear Structural Equation Models, Longitudinal Mediation With Latent Growth Models and Blended Learning in Biostatistics Education
Sullivan, Adam J. (2015-05-15)In chapter 1, we consider the biases that may arise when an unmeasured confounder is omitted from a structural equation model (SEM) and sensitivity analysis techniques to correct for such biases. We give an analysis of ... -
Sensitivity Analysis in Observational Research: Introducing the E-Value
VanderWeele, Tyler J.; Ding, Peng (American College of Physicians, 2017)Sensitivity analysis can be useful in assessing how robust associations are to potential unmeasured or uncontrolled confounding. In this paper we introduce a new measure that we call the “E-value,” a measure related to the ... -
Sensitivity Analysis Without Assumptions
Ding, Peng; VanderWeele, Tyler J. (Lippincott Williams & Wilkins, 2016)Unmeasured confounding may undermine the validity of causal inference with observational studies. Sensitivity analysis provides an attractive way to partially circumvent this issue by assessing the potential influence of ... -
Statistical Methods for Causal Mediation Analysis
Valeri, Linda (2013-03-14)Mediation analysis is a popular approach in the social an biomedical sciences to examine the extent to which the effect of an exposure on an outcome is through an intermediate variable (mediator) and the extent to which ...