Browsing by Author "Zhou, Wen"
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A novel role for RIP1 kinase in mediating TNFα production
Christofferson, D E; Li, Yan; Hitomi, J; Zhou, Wen; Upperman, C; Zhu, Hong; Gerber, S A; Gygi, Steven P.; Yuan, Junying (Nature Publishing Group, 2012)Receptor-interacting protein 1 (RIP1) is a Ser/Thr kinase with both kinase-dependent and kinase-independent roles in death receptor signaling. The kinase activity of RIP1 is required for necroptosis, a caspase-independent ... -
Regulation of Tumor Necrosis Factor-Induced Cell Death and Toll-Like Receptor-Mediated Activation of Macrophages by SPATA2
Zhou, Wen (2015-05-17)Cell death and innate immunity are interconnected events for multicellular organisms to defend against pathogenic microbes and restrict tissue damage. Macrophages constitute an important population of innate immunity. Their ...