Browsing by Author "Han, Xinbing"
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\(Leu128^{3.43}\) (L128) and \(Val247^{6.40}\) (V247) of CXCR1 Are Critical Amino Acid Residues for G Protein Coupling and Receptor Activation
Han, Xinbing; Tachado, Souvenir D.; Koziel, Henryk; Boisvert, William A. (Public Library of Science, 2012)CXCR1, a classic GPCR that binds IL-8, plays a key role in neutrophil activation and migration by activating phospholipase C (PLC)β through \(G\alpha_{15}\) and \(G\alpha_i\) which generates diacylglycerol and inositol ...