Now showing items 1-7 of 7

    • Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury 

      McKee, Ann C.; Cantu, Robert C.; Nowinski, Christopher J.; Hedley-Whyte, E. Tessa; Gavett, Brandon E.; Budson, Andrew E.; Santini, Veronica E.; Lee, Hyo-Soon; Kubilus, Caroline A.; Stern, Robert A. (Oxford University Press (OUP), 2009)
      Since the 1920s, it has been known that the repetitive brain trauma associated with boxing may produce a progressive neurological deterioration, originally termed “dementia pugilistica” and more recently, chronic traumatic ...
    • Cognitive status impacts age-related changes in attention to novel and target events in normal adults. 

      Daffner, Kirk R.; Chong, Hyemi; Riis, Jenna; Rentz, Dorene May; Wolk, David A.; Budson, Andrew E.; Holcomb, Phillip J. (American Psychological Association (APA), 2007)
      In this study, the authors investigated the relationship between the cognitive status of normal adults and age-related changes in attention to novel and target events. Old, middle-age, and young subjects, divided into ...
    • Electrophysiological Dissociation of Picture Versus Word Encoding: The Distinctiveness Heuristic as a Retrieval Orientation 

      Budson, Andrew E.; Droller, Daniel B.; Dodson, Chad S.; Schacter, Daniel L.; Rugg, Michael D.; Holcomb, Philip J.; Daffner, Kirk R. (Massachusetts Institute of Technology Press, 2005)
      Event-related potentials (ERPs) were used to investigate the neural processes underlying the distinctiveness heuristic— a response mode in which participants expect to remember vivid details of an experience and make ...
    • Frontal and Parietal Components of a Cerebral Network Mediating Voluntary Attention to Novel Events 

      Daffner, Kirk R.; Scinto, L. F. M.; Weitzman, A. M.; Faust, R.; Rentz, Dorene May; Budson, Andrew E.; Holcomb, P. J. (MIT Press - Journals, 2003)
      Despite the important role that attending to novel events plays in human behavior, there is limited information about the neuroanatomical underpinnings of this vital activity. This study investigated the relative contributions ...
    • Increased Responsiveness to Novelty is Associated with Successful Cognitive Aging 

      Daffner, Kirk R.; Ryan, Katherine K.; Williams, Danielle M.; Budson, Andrew E.; Rentz, Dorene May; Wolk, David A.; Holcomb, Phillip J. (MIT Press - Journals, 2006)
      The animal literature suggests that exposure to more complex, novel environments promotes neurogenesis and cognitive performance in older animals. Studies in humans indicate that participation in intellectually stimulating ...
    • Pathophysiology underlying diminished attention to novel events in patients with early AD 

      Daffner, Kirk R.; Rentz, Dorene May; Scinto, L. F.M.; Faust, R.; Budson, Andrew E.; Holcomb, P. J. (Ovid Technologies (Wolters Kluwer Health), 2001)
      Background: Patients with mild to moderate AD often are apathetic and fail to attend to novel aspects of their environment. Objective: To investigate the mechanisms underlying these changes by studying the novelty P3 ...
    • TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy 

      McKee, Ann C.; Gavett, Brandon E.; Stern, Robert A.; Nowinski, Christopher J.; Cantu, Robert C.; Kowall, Neil William; Perl, Daniel P.; Hedley-Whyte, E. Tessa; Price, Bruce Heimburger; Sullivan, Chris; Morin, Peter; Lee, Hyo-Soon; Kubilus, Caroline A.; Daneshvar, Daniel H.; Wulff, Megan; Budson, Andrew E. (Oxford University Press (OUP), 2010)
      Epidemiological evidence suggests that the incidence of amyotrophic lateral sclerosis is increased in association with head injury. Repetitive head injury is also associated with the development of chronic traumatic ...