Now showing items 1-20 of 31

    • An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population 

      Klein, Alison P.; Lindström, Sara; Mendelsohn, Julie B.; Steplowski, Emily; Arslan, Alan A.; Bueno-de-Mesquita, H. Bas; Fuchs, Charles S.; Gallinger, Steven; Gross, Myron; Helzlsouer, Kathy; Holly, Elizabeth A.; Jacobs, Eric J.; LaCroix, Andrea; Li, Donghui; Mandelson, Margaret T.; Olson, Sara H.; Petersen, Gloria M.; Risch, Harvey A.; Stolzenberg-Solomon, Rachael Z.; Zheng, Wei; Amundadottir, Laufey; Albanes, Demetrius; Allen, Naomi E.; Bamlet, William R.; Boutron-Ruault, Marie-Christine; Buring, Julie E.; Bracci, Paige M.; Canzian, Federico; Clipp, Sandra; Cotterchio, Michelle; Duell, Eric J.; Elena, Joanne; Gaziano, J. Michael; Giovannucci, Edward L.; Goggins, Michael; Hallmans, Göran; Hassan, Manal; Hutchinson, Amy; Hunter, David J.; Kooperberg, Charles; Kurtz, Robert C.; Liu, Simin; Overvad, Kim; Palli, Domenico; Patel, Alpa V.; Rabe, Kari G.; Shu, Xiao-Ou; Slimani, Nadia; Tobias, Geoffrey S.; Trichopoulos, Dimitrios; Van Den Eeden, Stephen K.; Vineis, Paolo; Virtamo, Jarmo; Wactawski-Wende, Jean; Wolpin, Brian M.; Yu, Herbert; Yu, Kai; Zeleniuch-Jacquotte, Anne; Chanock, Stephen J.; Hoover, Robert N.; Hartge, Patricia; Kraft, Peter (Public Library of Science, 2013)
      Purpose We developed an absolute risk model to identify individuals in the general population at elevated risk of pancreatic cancer. Patients and Methods Using data on 3,349 cases and 3,654 controls from the PanScan ...
    • Additive influence of genetic predisposition and conventional risk factors in the incidence of coronary heart disease: a population-based study in Greece 

      Yiannakouris, Nikos; Katsoulis, Michail; Trichopoulou, Antonia; Ordovas, Jose M; Trichopoulos, Dimitrios (BMJ Publishing Group, 2014)
      Objectives: An additive genetic risk score (GRS) for coronary heart disease (CHD) has previously been associated with incident CHD in the population-based Greek European Prospective Investigation into Cancer and nutrition ...
    • Adiposity, Hormone Replacement Therapy Use and Breast Cancer Risk by Age and Hormone Receptor Status: A Large Prospective Cohort Study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure Filskov; Overvad, Kim; Clavel-Chapelon, Françoise; Fournier, Agnès; Fagherazzi, Guy; Rohrmann, Sabine; Teucher, Birgit; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Quirós, José Ramón; Buckland, Genevieve; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Ardanaz, Eva; Sund, Malin; Lenner, Per; Bueno-de-Mesquita, Bas; van Gils, Carla H; Peeters, Petra HM; Krum-Hansen, Sanda; Gram, Inger Torhild; Lund, Eiliv; Khaw, Kay-Tee; Wareham, Nick; Allen, Naomi E; Key, Timothy J; Romieu, Isabelle; Rinaldi, Sabina; Siddiq, Afshan; Riboli, Elio; Kaaks, Rudolf; Lagiou, Pagona; Trichopoulos, Dimitrios; Cox, David (BioMed Central, 2012)
      Introduction: Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with hormone-receptor ...
    • Anatomy of Health Effects of Mediterranean Diet: Greek EPIC Prospective Cohort Study 

      Trichopoulou, Antonia; Bamia, Christina; Trichopoulos, Dimitrios (BMJ Publishing Group, 2009)
      Objective: To investigate the relative importance of the individual components of the Mediterranean diet in generating the inverse association of increased adherence to this diet and overall mortality. Design: Prospective ...
    • Association between Pre-Diagnostic Circulating Vitamin D Concentration and Risk of Colorectal Cancer in European Populations: a Nested Case-Control Study 

      Jenab, Mazda; Bueno-de-Mesquita, H Bas; Ferrari, Pietro; van Duijnhoven, Franzel J B; Norat, Teresa; Pischon, Tobias; Jansen, Eugène H J M; Slimani, Nadia; Byrnes, Graham; Rinaldi, Sabina; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Morois, Sophie; Kaaks, Rudolf; Linseisen, Jakob; Boeing, Heiner; Bergmann, Manuela M; Trichopoulou, Antonia; Misirli, Gesthimani; Berrino, Franco; Vineis, Paolo; Panico, Salvatore; Palli, Domenico; Tumino, Rosario; Ros, Martine M; van Gils, Carla H; Peeters, Petra H; Brustad, Magritt; Lund, Eiliv; Tormo, María-José; Ardanaz, Eva; Rodríguez, Laudina; Sánchez, Maria-José; Dorronsoro, Miren; Gonzalez, Carlos A; Hallmans, Göran; Palmqvist, Richard; Roddam, Andrew; Key, Timothy J; Khaw, Kay-Tee; Autier, Philippe; Hainaut, Pierre; Riboli, Elio; Trichopoulos, Dimitrios (BMJ Publishing Group Ltd., 2010)
      Objective: To examine the association between pre-diagnostic circulating vitamin D concentration, dietary intake of vitamin D and calcium, and the risk of colorectal cancer in European populations. Design Nested case-control ...
    • Circulating Biomarkers of One-Carbon Metabolism in Relation to Renal Cell Carcinoma Incidence and Survival 

      Johansson, Mattias; Fanidi, Anouar; Muller, David C.; Bassett, Julie K.; Midttun, Øivind; Vollset, Stein Emil; Travis, Ruth C.; Palli, Domenico; Mattiello, Amalia; Sieri, Sabina; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Ljungberg, Börje; Hallmans, Göran; Weiderpass, Elisabete; Skeie, Guri; González, Carlos A.; Dorronsoro, Miren; Peeters, Petra H.; Bueno-de-Mesquita, H. B(as).; Ros, Martine M.; Boutron Ruault, Marie-Christine; Fagherazzi, Guy; Clavel, Françoise; Sánchez, María-José; Gurrea, Aurelio Barricarte; Navarro, Carmen; Quiros, J. Ramon; Overvad, Kim; Tjønneland, Anne; Aleksandrova, Krassimira; Vineis, Paolo; Gunter, Marc J.; Kaaks, Rudolf; Giles, Graham; Relton, Caroline; Riboli, Elio; Boeing, Heiner; Ueland, Per Magne; Severi, Gianluca; Brennan, Paul (Oxford University Press, 2014)
      Background: The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. Methods: The ...
    • Circulating Fatty Acids and Prostate Cancer Risk: Individual Participant Meta-Analysis of Prospective Studies 

      Crowe, Francesca L.; Appleby, Paul N.; Travis, Ruth C.; Barnett, Matt; Brasky, Theodore M.; Bueno-de-Mesquita, H. Bas; Chajes, Veronique; Chavarro, Jorge E.; Chirlaque, Maria-Dolores; English, Dallas R.; Gibson, Robert A.; Giles, Graham G.; Goodman, Gary E.; Henning, Susanne M.; Kaaks, Rudolf; King, Irena B.; Kolonel, Lawrence N.; Kristal, Alan R.; Neuhouser, Marian L.; Park, Song-Yi; Severi, Gianluca; Siddiq, Afshan; Stampfer, Meir J.; Stattin, Pär; Tangen, Catherine M.; Tjønneland, Anne; Trichopoulos, Dimitrios; Tumino, Rosario; Wilkens, Lynne R.; Key, Timothy J.; Allen, Naomi E. (Oxford University Press, 2014)
      Background: Individual studies have suggested that some circulating fatty acids are associated with prostate cancer risk, but have not been large enough to provide precise estimates of associations, particularly by stage ...
    • Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study 

      Aleksandrova, Krasimira; Pischon, Tobias; Jenab, Mazda; Bueno-de-Mesquita, H Bas; Fedirko, Veronika; Norat, Teresa; Romaguera, Dora; Knüppel, Sven; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Kaaks, Rudolf; Li, Kuanrong; Tjønneland, Anne; Overvad, Kim; Quirós, José Ramón; Buckland, Genevieve; Sánchez, María José; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nicholas J; Bradbury, Kathryn E; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Siersema, Peter D; Peeters, Petra HM; Ljuslinder, Ingrid; Johansson, Ingegerd; Ericson, Ulrika; Ohlsson, Bodil; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Rinaldi, Sabina; Romieu, Isabelle; Kong, Joyce; Gunter, Marc J; Ward, Heather A; Riboli, Elio; Boeing, Heiner (BioMed Central, 2014)
      Background: Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little is known about their joint effects. The ...
    • Consumption of Dairy Products and Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, Bas; Skeie, Guri; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Boutron-Ruault, Marie Christine; Clavel-Chapelon, Françoise; Nailler, Laura; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H. M.; Dik, Vincent K.; Weiderpass, Elisabete; Lund, Eiliv; Garcia, Jose Ramon Quiros; Zamora-Ros, Raul; Pérez, Maria José Sánchez; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Manjer, Jonas; Almquist, Martin; Johansson, Ingegerd; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Gunter, Marc J.; Riboli, Elio (Public Library of Science, 2013)
      Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the ...
    • Development and Validation of a Risk Score Predicting Substantial Weight Gain over 5 Years in Middle-Aged European Men and Women 

      Steffen, Annika; Sørensen, Thorkild I A.; Knüppel, Sven; Travier, Noemie; Sánchez, María-José; Huerta, José María; Quirós, J. Ramón; Ardanaz, Eva; Dorronsoro, Miren; Teucher, Birgit; Li, Kuanrong; Bueno-de-Mesquita, H. Bas; van der A, Daphne; Mattiello, Amalia; Palli, Domenico; Tumino, Rosario; Krogh, Vittorio; Vineis, Paolo; Trichopoulou, Antonia; Orfanos, Philippos; Trichopoulos, Dimitrios; Hedblad, Bo; Wallström, Peter; Overvad, Kim; Halkjær, Jytte; Tjønneland, Anne; Fagherazzi, Guy; Dartois, Laureen; Crowe, Francesca; Khaw, Kay-Tee; Wareham, Nick; Middleton, Lefkos; May, Anne M.; Peeters, Petra H. M.; Boeing, Heiner (Public Library of Science, 2013)
      Background: Identifying individuals at high risk of excess weight gain may help targeting prevention efforts at those at risk of various metabolic diseases associated with weight gain. Our aim was to develop a risk score ...
    • Dietary Fibre Intake and Risks of Cancers of the Colon and Rectum in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, Bas; Skeie, Guri; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Racine, Antoine; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Siersema, Peter; van Duijnhoven, Franzel; Peeters, Petra H. M.; Hjartaker, Anette; Engeset, Dagrun; González, Carlos A.; Sánchez, Maria-José; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Quirós, José R.; Sonestedt, Emily; Ericson, Ulrika; Nilsson, Lena; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Wark, Petra A.; Chuang, Shu-Chun; Riboli, Elio (Public Library of Science, 2012)
      Background: Earlier analyses within the EPIC study showed that dietary fibre intake was inversely associated with colorectal cancer risk, but results from some large cohort studies do not support this finding. We explored ...
    • Genetic Variability of the mTOR Pathway and Prostate Cancer Risk in the European Prospective Investigation on Cancer (EPIC) 

      Campa, Daniele; Stein, Angelika; Dostal, Lucie; Boeing, Heiner; Pischon, Tobias; Roswall, Nina; Overvad, Kim; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nicholas; Travis, Ruth C.; Allen, Naomi E.; Trichopoulou, Antonia; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; van Kranen, Henk; Bueno-de-Mesquita, H. Bas; Johansson, Mattias; Romieu, Isabelle; Jenab, Mazda; Siddiq, Afshan; Riboli, Elio; Canzian, Federico; Kaaks, Rudolf; Agoulnik, Irina; Hüsing, Anna; Tjønnelan, Anne; Østergaard, Jane Nautrup; Rodríguez, Laudina; Sala, Núria; Sánchez, Maria-José; Larrañaga, Nerea; Huerta, José-Maria; Hallmans, Göran; Cox, David G.; Lagiou, Pagona; Trichopoulos, Dimitrios (Public Library of Science, 2011)
      The mTOR (mammalian target of rapamycin) signal transduction pathway integrates various signals, regulating ribosome biogenesis and protein synthesis as a function of available energy and amino acids, and assuring an ...
    • Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma 

      Cerhan, James R.; Berndt, Sonja I.; Vijai, Joseph; Ghesquières, Hervé; McKay, James; Wang, Sophia S.; Wang, Zhaoming; Yeager, Meredith; Conde, Lucia; de Bakker, Paul; Nieters, Alexandra; Cox, David; Burdett, Laurie; Monnereau, Alain; Flowers, Christopher R.; De Roos, Anneclaire J.; Brooks-Wilson, Angela R.; Lan, Qing; Severi, Gianluca; Melbye, Mads; Gu, Jian; Jackson, Rebecca D.; Kane, Eleanor; Teras, Lauren R.; Purdue, Mark P.; Vajdic, Claire M.; Spinelli, John J.; Giles, Graham G.; Albanes, Demetrius; Kelly, Rachel; Zucca, Mariagrazia; Bertrand, Kimberly Anne; Zeleniuch-Jacquotte, Anne; Lawrence, Charles; Hutchinson, Amy; Zhi, Degui; Habermann, Thomas M.; Link, Brian K.; Novak, Anne J.; Dogan, Ahmet; Asmann, Yan W.; Liebow, Mark; Thompson, Carrie A.; Ansell, Stephen M.; Witzig, Thomas E.; Weiner, George J.; Veron, Amelie S.; Zelenika, Diana; Tilly, Hervé; Haioun, Corinne; Molina, Thierry Jo; Hjalgrim, Henrik; Glimelius, Bengt; Adami, Hans-Olov; Bracci, Paige M.; Riby, Jacques; Smith, Martyn T.; Holly, Elizabeth A.; Cozen, Wendy; Hartge, Patricia; Morton, Lindsay M.; Severson, Richard K.; Tinker, Lesley F.; North, Kari E.; Becker, Nikolaus; Benavente, Yolanda; Boffetta, Paolo; Brennan, Paul; Foretova, Lenka; Maynadie, Marc; Staines, Anthony; Lightfoot, Tracy; Crouch, Simon; Smith, Alex; Roman, Eve; Diver, W. Ryan; Offit, Kenneth; Zelenetz, Andrew; Klein, Robert J.; Villano, Danylo J.; Zheng, Tongzhang; Zhang, Yawei; Holford, Theodore R.; Kricker, Anne; Turner, Jenny; Southey, Melissa C.; Clavel, Jacqueline; Virtamo, Jarmo; Weinstein, Stephanie; Riboli, Elio; Vineis, Paolo; Kaaks, Rudolph; Trichopoulos, Dimitrios; Vermeulen, Roel C. H.; Boeing, Heiner; Tjonneland, Anne; Angelucci, Emanuele; Di Lollo, Simonetta; Rais, Marco; Birmann, Brenda Melanie; Laden, Francine; Giovannucci, Edward L.; Kraft, Phillip L.; Huang, Jinyan; Ma, Baoshan; Ye, Yuanqing; Chiu, Brian C. H.; Sampson, Joshua; Liang, Liming; Park, Ju-Hyun; Chung, Charles C.; Weisenburger, Dennis D.; Chatterjee, Nilanjan; Fraumeni Jr, Joseph F.; Slager, Susan L.; Wu, Xifeng; de Sanjose, Silvia; Smedby, Karin E.; Salles, Gilles; Skibola, Christine F.; Rothman, Nathaniel; Chanock, Stephen J. (Nature Publishing Group, 2014)
      Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype and is clinically aggressive. To identify genetic susceptibility loci for DLBCL, we conducted a meta-analysis of three new genome-wide association ...
    • A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium 

      McKay, James D.; Truong, Therese; Gaborieau, Valerie; Chabrier, Amelie; Chuang, Shu-Chun; Byrnes, Graham; Zaridze, David; Shangina, Oxana; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Bucur, Alexandru; Bencko, Vladimir; Holcatova, Ivana; Janout, Vladimir; Foretova, Lenka; Benhamou, Simone; Bouchardy, Christine; Ahrens, Wolfgang; Merletti, Franco; Richiardi, Lorenzo; Talamini, Renato; Barzan, Luigi; Kjaerheim, Kristina; Macfarlane, Gary J.; Macfarlane, Tatiana V.; Simonato, Lorenzo; Canova, Cristina; Agudo, Antonio; Lowry, Ray; Conway, David I.; McKinney, Patricia A.; Toner, Mary E.; Znaor, Ariana; Curado, Maria Paula; Koifman, Sergio; Menezes, Ana; Boccia, Stefania; Cadoni, Gabriella; Arzani, Dario; Olshan, Andrew F.; Weissler, Mark C.; Funkhouser, William K.; Luo, Jingchun; Trubicka, Joanna; Lener, Marcin; Oszutowska, Dorota; Schwartz, Stephen M.; Fish, Sherianne; Doody, David R.; Muscat, Joshua E.; Lazarus, Philip; Gallagher, Carla J.; Chang, Shen-Chih; Zhang, Zuo-Feng; Wei, Qingyi; Sturgis, Erich M.; Wang, Li-E; Franceschi, Silvia; Herrero, Rolando; Kelsey, Karl T.; McClean, Michael D.; Marsit, Carmen J.; Nelson, Heather H.; Romkes, Marjorie; Buch, Shama; Nukui, Tomoko; Zhong, Shilong; Lacko, Martin; Manni, Johannes J.; Peters, Wilbert H. M.; Hung, Rayjean J.; Goodman, Gary E.; Liloglou, Triantafillos; Vineis, Paolo; Clavel-Chapelon, Francoise; Palli, Domenico; Tumino, Rosario; Krogh, Vittorio; Panico, Salvatore; Navarro, Carmen; Ardanaz, Eva; Khaw, Kay-Tee; Key, Timothy; Bueno-de-Mesquita, H. Bas; Peeters, Petra H. M.; Trichopoulou, Antonia; Linseisen, Jakob; Boeing, Heiner; Overvad, Kim; Kumle, Merethe; Riboli, Elio; Metspalu, Andres; Zelenika, Diana; Boland, Anne; Delepine, Marc; Foglio, Mario; Lechner, Doris; Gut, Ivo G.; Galan, Pilar; Heath, Simon; Hashibe, Mia; Hayes, Richard B.; Lathrop, Mark; Brennan, Paul; Horwitz, Marshall S.; Lagiou, Pagona; Trichopoulos, Dimitrios; Castellsagué, Xavier; Wünsch-Filho, Victor; Neto, José Eluf; Garrote, Leticia Fernández; Lubiński, Jan; Chen, Chu; McLaughin, John; Vatten, Lars Johan; Njølstad, Inger; Field, John K; González, Carlos A; Quirós, J. Ramón; Martínez, Carmen; Larrañaga, Nerea; Hallmans, Göran; Tjønneland, Anne; Välk, Kristjan; Vooder, Tõnu; Blanché, Hélène; Boffetta, Paolo (Public Library of Science, 2011)
      Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation ...
    • A Genome-Wide “Pleiotropy Scan” Does Not Identify New Susceptibility Loci for Estrogen Receptor Negative Breast Cancer 

      Campa, Daniele; Barrdahl, Myrto; Tsilidis, Konstantinos K.; Severi, Gianluca; Diver, W. Ryan; Siddiq, Afshan; Chanock, Stephen; Hoover, Robert N.; Ziegler, Regina G.; Berg, Christine D.; Buys, Saundra S.; Haiman, Christopher A.; Henderson, Brian E.; Schumacher, Fredrick R.; Le Marchand, Loïc; Flesch-Janys, Dieter; Lindström, Sara; Hunter, David J.; Hankinson, Susan E.; Willett, Walter C.; Kraft, Peter; Cox, David G.; Khaw, Kay-Tee; Tjønneland, Anne; Dossus, Laure; Trichopoulos, Dimitrios; Panico, Salvatore; van Gils, Carla H.; Weiderpass, Elisabete; Barricarte, Aurelio; Sund, Malin; Gaudet, Mia M.; Giles, Graham; Southey, Melissa; Baglietto, Laura; Chang-Claude, Jenny; Kaaks, Rudolf; Canzian, Federico (Public Library of Science, 2014)
      Approximately 15–30% of all breast cancer tumors are estrogen receptor negative (ER−). Compared with ER-positive (ER+) disease they have an earlier age at onset and worse prognosis. Despite the vast number of risk variants ...
    • Healthy Lifestyle and Risk of Cancer in the European Prospective Investigation Into Cancer and Nutrition Cohort Study 

      McKenzie, Fiona; Biessy, Carine; Ferrari, Pietro; Freisling, Heinz; Rinaldi, Sabina; Chajès, Veronique; Dahm, Christina C.; Overvad, Kim; Dossus, Laure; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Bueno-de-Mesquita, H. Bas; May, Anne; Peeters, Petra H.; Weiderpass, Elisabete; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Ericson, Ulrika; Wirfält, Elisabet; Travis, Ruth C.; Romieu, Isabelle (Wolters Kluwer Health, 2016)
      Abstract It has been estimated that at least a third of the most common cancers are related to lifestyle and as such are preventable. Key modifiable lifestyle factors have been individually associated with cancer risk; ...
    • Inflammatory and metabolic biomarkers and risk of liver and biliary tract cancer 

      Aleksandrova, Krasimira; Boeing, Heiner; Nöthlings, Ute; Jenab, Mazda; Fedirko, Veronika; Kaaks, Rudolf; Lukanova, Annekatrin; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Boffetta, Paolo; Trepo, Elisabeth; Westhpal, Sabine; Duarte-Salles, Talita; Stepien, Magdalena; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Boutron-Ruault, Marie-Christine; Dossus, Laure; Racine, Antoine; Lagiou, Pagona; Bamia, Christina; Benetou, Vassiliki; Agnoli, Claudia; Palli, Domenico; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, Bas; Peeters, Petra H; Gram, Inger Torhild; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J Ramón; Agudo, Antonio; Sánchez, María-José; Gavrila, Diana; Barricarte, Aurelio; Dorronsoro, Miren; Ohlsson, Bodil; Lindkvist, Björn; Johansson, Anders; Sund, Malin; Khaw, Kay-Tee; Wareham, Nicholas; Travis, Ruth C; Riboli, Elio; Pischon, Tobias (BlackWell Publishing Ltd, 2014)
      Obesity and associated metabolic disorders have been implicated in liver carcinogenesis; however, there are little data on the role of obesity-related biomarkers on liver cancer risk. We studied prospectively the association ...
    • Intrauterine Environment, Mammary Gland Mass and Breast Cancer Risk 

      Trichopoulos, Dimitrios (BioMed Central, 2002)
      Two intimately linked hypotheses on breast cancer etiology are described. The main postulate of the first hypothesis is that higher levels of pregnancy estrogens and other hormones favor the generation of a higher number ...
    • Lifetime alcohol use and overall and cause-specific mortality in the European Prospective Investigation into Cancer and nutrition (EPIC) study 

      Ferrari, Pietro; Licaj, Idlir; Muller, David C; Kragh Andersen, Per; Johansson, Mattias; Boeing, Heiner; Weiderpass, Elisabete; Dossus, Laure; Dartois, Laureen; Fagherazzi, Guy; Bradbury, Kathryn E; Khaw, Kay-Tee; Wareham, Nick; Duell, Eric J; Barricarte, Aurelio; Molina-Montes, Esther; Sanchez, Carmen Navarro; Arriola, Larraitz; Wallström, Peter; Tjønneland, Anne; Olsen, Anja; Trichopoulou, Antonia; Benetou, Vasiliki; Trichopoulos, Dimitrios; Tumino, Rosario; Agnoli, Claudia; Sacerdote, Carlotta; Palli, Domenico; Li, Kuanrong; Kaaks, Rudolf; Peeters, Petra; Beulens, Joline WJ; Nunes, Luciana; Gunter, Marc; Norat, Teresa; Overvad, Kim; Brennan, Paul; Riboli, Elio; Romieu, Isabelle (BMJ Publishing Group, 2014)
      Objectives: To investigate the role of factors that modulate the association between alcohol and mortality, and to provide estimates of absolute risk of death. Design: The European Prospective Investigation into Cancer and ...
    • Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study 

      Lagiou, Pagona; Sandin, Sven; Lof, Marie; Trichopoulos, Dimitrios; Adami, Hans-Olov; Weiderpass, Elisabete (BMJ Publishing Group Ltd., 2012)
      Objective: To study the long term consequences of low carbohydrate diets, generally characterised by concomitant increases in protein intake, on cardiovascular health. Design Prospective cohort study. Setting Uppsala, ...