Now showing items 1-2 of 2

    • [18F]-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography of LAPC4-CR Castration-Resistant Prostate Cancer Xenograft Model in Soft Tissue Compartments1 

      McCall, Keisha C.; Cheng, Su-Chun; Huang, Ying; Kohl, Nancy E.; Tupper, Tanya; Van den Abbeele, Annick D.; Zukotynski, Katherine A.; Sweeney, Christopher J. (Neoplasia Press, 2015)
      Preclinical xenograft models have contributed to advancing our understanding of the molecular basis of prostate cancer and to the development of targeted therapy. However, traditional preclinical in vivo techniques using ...
    • Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors 

      Demetri, George Daniel; von Mehren, Margaret; Blanke, Charles D.; Van Den Abbeele, Annick Diane; Eisenberg, Burton; Roberts, Peter J.; Heinrich, Michael C.; Tuveson, David A.; Singer, Samuel; Janicek, Milos; Fletcher, Jonathan A.; Silverman, Stuart George; Silberman, Sandra L.; Capdeville, Renaud; Kiese, Beate; Peng, Bin; Dimitrijevic, Sasa; Druker, Brian J.; Corless, Christopher; Fletcher, Christopher D.M.; Joensuu, Heikki (New England Journal of Medicine (NEJM/MMS), 2002)
      Background Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis of gastrointestinal stromal tumors. Imatinib mesylate, a selective tyrosine kinase inhibitor, has been shown in preclinical ...