Browsing by Author "Kirby, James"
Now showing items 1-3 of 3
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The Alzheimer's Disease-Associated Amyloid \(\beta\)-Protein Is an Antimicrobial Peptide
Soscia, Stephanie; Kirby, James Edward; Washicosky, Kevin J.; Tucker, Stephanie; Ingelsson, Martin; Hyman, Bradley Theodore; Burton, Mark A.; Duong, Scott; Tanzi, Rudolph Emile; Moir, Robert D.; Goldstein, Lee E. (Public Library of Science, 2010)Background: The amyloid \(\beta\)-protein (A\(\beta\)) is believed to be the key mediator of Alzheimer's disease (AD) pathology. A\(\beta\) is most often characterized as an incidental catabolic byproduct that lacks a ... -
The Alzheimer’s Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide
Kirby, James Edward; Washicosky, Kevin J.; Tucker, Stephanie M.; Ingelsson, Martin; Hyman, Bradley Theodore; Burton, Mark A.; Goldstein, Lee E.; Duong, Scott; Tanzi, Rudolph Emile; Moir, Robert D. (Public Library of Science, 2010)Background: The amyloid β-protein (Aβ) is believed to be the key mediator of Alzheimer's disease (AD) pathology. Aβ is most often characterized as an incidental catabolic byproduct that lacks a normal physiological role. ... -
Investigation of a Candida guilliermondii Pseudo-Outbreak Reveals a Novel Source of Laboratory Contamination
Kirby, James; Branch-Elliman, Westyn; LaSalvia, Mary; Longhi, Lorinda; MacKechnie, Matthew; Urman, Grigoriy; Baldini, Linda M.; Muriel, Fatima R.; Sullivan, Bernadette; Yassa, David; Gold, Howard; Wagner, Trevor K.; Diekema, Daniel J.; Wright, Sharon (American Society for Microbiology, 2017-04)Candida guilliermondii was isolated from sterile specimens with increasing frequency over a several-month period despite a paucity of clinical evidence suggesting true Candida infections. However, a health care-associated ...