Browsing by Author "Yang, Jason"
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Bacterial Metabolic State More Accurately Predicts Antibiotic Lethality Than Growth Rate
Lopatkin, Allison; Stokes, Jonathan; Zheng, Erica; Yang, Jason; Takahashi, Melissa; You, Lingchong; Collins, James (Springer Science and Business Media LLC, 2019-08-26)Growth rate and metabolic state have been separately shown to affect antibiotic efficacy1–3. However, the two are interrelated since bacterial growth inherently imposes a metabolic burden4; thus, determining individual ...