Now showing items 1-4 of 4

    • Biology of Type 2 Phosphatidylinositol-5-Phosphate 4-Kinase 

      Shim, Hyeseok (2015-09-22)
      Type 2 phosphatidylinositol-5-phosphate 4-kinase (PI5P4K) converts phosphatidylinositol-5-phosphate to phosphatidylinositol-4,5-bisphosphate. Mammals have three genes, PIP4K2A, PIP4K2B and PIP4K2C that encode the enzymes ...
    • CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies 

      Widemann, Brigitte C.; Acosta, Maria T.; Ammoun, Sylvia; Belzberg, Allan J.; Bernards, Andre; Blakeley, Jaishri; Bretscher, Antony; Cichowski, Karen Marie; Clapp, D. Wade; Dombi, Eva; Evans, Gareth D.; Ferner, Rosalie; Fernandez-Valle, Cristina; Fisher, Michael J.; Giovannini, Marco; Gutmann, David H.; Hanemann, C. Oliver; Hennigan, Robert; Huson, Susan; Ingram, David; Kissil, Joe; Korf, Bruce R.; Legius, Eric; Packer, Roger J.; McClatchey, Andrea I.; McCormick, Frank; North, Kathryn; Pehrsson, Minja; Plotkin, Scott Randall; Ramesh, Vijaya; Ratner, Nancy; Schirmer, Susann; Sherman, Larry; Schorry, Elizabeth; Stevenson, David; Stewart, Douglas C; Ullrich, Nicole Johnson; Bakker, Annette C.; Morrison, Helen (Wiley-Blackwell, 2014)
      The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases NF1, NF2, and schwannomatosis. The NFs affect more people worldwide than Duchenne muscular dystrophy and Huntington's ...
    • Identification and Analysis of a New Tumor and Metastasis Suppressor Gene, RASAL2 

      McLaughlin, Sara Koenig (2013-10-08)
      RAS is one of the most commonly mutated genes in human cancer; its aberrant activation drives tumor cell proliferation and survival. However, RAS mutations are rare in some cancers, including breast cancer, even though ...
    • Neurofibromatosis 2011: A Report of the Children’s Tumor Foundation Annual Meeting 

      Kalamarides, Michel; Acosta, Maria T.; Babovic-Vuksanovic, Dusica; Carpen, Olli; Gareth Evans, D.; Giancotti, Filippo; Oliver Hanemann, C.; Ingram, David; Lloyd, Alison C.; Mayes, Debra A.; Messiaen, Ludwine; Morrison, Helen; North, Kathryn; Packer, Roger; Pan, Duojia; Upadhyaya, Meena; Viskochil, David; Wallace, Margret R.; Hunter-Schaedle, Kim; Ratner, Nancy; Cichowski, Karen Marie; Stemmer-Rachamimov, Anat (Springer-Verlag, 2012)
      The 2011 annual meeting of the Children’s Tumor Foundation, the annual gathering of the neurofibromatosis (NF) research and clinical communities, was attended by 330 participants who discussed integration of new signaling ...