Browsing by Author "David, William"

Now showing items 1-4 of 4

    • Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis 

      Berry, James Dale; Shefner, Jeremy M.; Conwit, Robin; Schoenfeld, David Alan; Keroack, Myles; Felsenstein, Donna; Krivickas, Lisa; David, William Samuel; Vriesendorp, Francine; Pestronk, Alan; Caress, James B.; Katz, Jonathan; Simpson, Ericka; Rosenfeld, Jeffrey; Pascuzzi, Robert; Glass, Jonathan; Rezania, Kourosh; Rothstein, Jeffrey D.; Greenblatt, David J.; Cudkowicz, Merit Ester (Public Library of Science, 2013)
      Objectives: Ceftriaxone increases expression of the astrocytic glutamate transporter, EAAT2, which might protect from glutamate-mediated excitotoxicity. A trial using a novel three stage nonstop design, incorporating Phases ...

    • Electrical impedance myography as a biomarker to assess ALS progression 

      Rutkove, Seward Brian; Caress, James B.; Cartwright, Michael S.; Burns, Ted M.; Warder, Judy; David, William Samuel; Goyal, Namita; Maragakis, Nicholas J.; Clawson, Lora; Benatar, Michael; Usher, Sharon; Sharma, Khema R.; Gautam, Shiva; Narayanaswami, Pushpa; Raynor, Elizabeth M; Watson, Mary Lou; Shefner, Jeremy M. (Informa UK Limited, 2012)
      Electrical impedance myography (EIM), a non-invasive, electrophysiological technique, has preliminarily shown value as an ALS biomarker. Here we perform a multicenter study to further assess EIM’s potential for tracking ...

    • Evidence-based guideline summary: Diagnosis and treatment of limb-girdle and distal dystrophies: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the Practice Issues Review Panel of the American Association of Neuromuscular & Electrodiagnostic Medicine 

      Narayanaswami, Pushpa; Weiss, Michael; Selcen, Duygu; David, William Samuel; Raynor, Elizabeth M; Carter, Gregory; Wicklund, Matthew; Barohn, Richard J.; Ensrud, Erik; Griggs, R. C.; Gronseth, Gary; Amato, Anthony A. (Ovid Technologies (Wolters Kluwer Health), 2014)
      Objective: To review the current evidence and make practice recommendations regarding the diagnosis and treatment of limb-girdle muscular dystrophies (LGMDs). Methods: Systematic review and practice recommendation ...

    • Quality improvement in neurology: Muscular dystrophy quality measures 

      Narayanaswami, Pushpa; Dubinsky, Richard; Wang, David; Gjorvad, Gina; David, William Samuel; Finder, Jonathan; Smith, Benn; Cheng, Jianguo; Shapiro, Frederic; Mellion, Michelle; Spurney, Christopher; Wolff, Jodi; England, John (Ovid Technologies (Wolters Kluwer Health), 2015)
      The muscular dystrophies (MDs) are a heterogeneous group of genetically determined myopathies. Identification of underlying genetic defects has demonstrated that MDs exhibit significant phenotypic and genetic heterogeneity. ...