Now showing items 1-3 of 3

    • Discovery and Characterization of Novel smORF-Encoded Polypeptides (SEPs) 

      Ma, Jiao (2016-01-04)
      Peptides and small proteins have essential physiological roles including metabolism (insulin), sleep (orexin), and stress (corticotropin-releasing hormone). Recent exploration of the human genome and proteome has revealed ...
    • Discovery of Human sORF-Encoded Polypeptides (SEPs) in Cell Lines and Tissue 

      Ma, Jiao; Ward, Carl C.; Jungreis, Irwin; Slavoff, Sarah A.; Schwaid, Adam G.; Neveu, John; Budnik, Bogdan A.; Kellis, Manolis; Saghatelian, Alan (American Chemical Society, 2014)
      The existence of nonannotated protein-coding human short open reading frames (sORFs) has been revealed through the direct detection of their sORF-encoded polypeptide (SEP) products. The discovery of novel SEPs increases ...
    • Peptidomic discovery of short open reading frame-encoded peptides in human cells 

      Slavoff, Sarah A.; Mitchell, Andrew J.; Schwaid, Adam G.; Cabili, Moran N.; Ma, Jiao; Levin, Joshua Z.; Karger, Amir; Budnik, Bogdan A.; Rinn, John L.; Saghatelian, Alan (2013)
      The amount of the transcriptome that is translated into polypeptides is of fundamental importance. We developed a peptidomic strategy to detect short ORF (sORF)-encoded polypeptides (SEPs) in human cells. We identified 90 ...