Browsing by Author "Liu, Yang"
Now showing items 1-4 of 4
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Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells?
Kam, Wendy R.; Liu, Yang; Ding, Juan; Sullivan, David A. (The Association for Research in Vision and Ophthalmology, 2016)Purpose Researchers have hypothesized that treatment with cyclosporine A (CyA), interleukin-1 receptor antagonists (IL-1RA; e.g., anakinra), P2Y2 receptor agonists (e.g., uridine triphosphate; UTP), and rebamipide may ... -
Growth Hormone Influence on the Morphology and Size of the Mouse Meibomian Gland
Liu, Yang; Knop, Erich; Knop, Nadja; Sullivan, David A.; List, Edward O.; Kopchick, John J.; Kam, Wendy R.; Ding, Juan (Hindawi Publishing Corporation, 2016)Purpose. We hypothesize that growth hormone (GH) plays a significant role in the regulation of the meibomian gland. To test our hypothesis, we examined the influence of GH on mouse meibomian gland structure. Methods. We ... -
IL-1\(\beta\) Is Upregulated in the Diabetic Retina and Retinal Vessels: Cell-Specific Effect of High Glucose and IL-1\(\beta\) Autostimulation
Liu, Yang; Biarnés Costa, Montserrat; Gerhardinger, Chiara (Public Library of Science, 2012)Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1\(\beta\)-driven neuroinflammation in the pathogenesis of diabetic retinopathy. IL-1\(\beta\) is well known for its role in ... -
Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development
Giannikou, Krinio; Malinowska, Izabela A.; Pugh, Trevor J.; Yan, Rachel; Tseng, Yuen-Yi; Oh, Coyin; Kim, Jaegil; Tyburczy, Magdalena E.; Chekaluk, Yvonne; Liu, Yang; Alesi, Nicola; Finlay, Geraldine A.; Wu, Chin-Lee; Signoretti, Sabina; Meyerson, Matthew; Getz, Gad; Boehm, Jesse S.; Henske, Elizabeth P.; Kwiatkowski, David J. (Public Library of Science, 2016)Renal angiomyolipoma is a kidney tumor in the perivascular epithelioid (PEComa) family that is common in patients with Tuberous Sclerosis Complex (TSC) and Lymphangioleiomyomatosis (LAM) but occurs rarely sporadically. ...