Browsing by Author "Tao, Yong"

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Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo

Shu, Yilai; Tao, Yong; Li, Wenyan; Shen, Jun; Wang, Zhengmin; Chen, Zheng-Yi (Hindawi Publishing Corporation, 2016)

Mammalian inner ear harbors diverse cell types that are essential for hearing and balance. Adenovirus is one of the major vectors to deliver genes into the inner ear for functional studies and hair cell regeneration. To ...
Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo

Li, Margie; Tao, Yong; Shu, Yilai; LaRochelle, Jonathan R.; Steinauer, Angela; Thompson, David; Schepartz, Alanna; Chen, Zheng-Yi; Liu, David Ruchien (American Chemical Society (ACS), 2015)

The in efficient delivery of proteins into mammalian cells remains a major barrier to realizing the therapeutic potential of many proteins. We and others have previously shown that superpositively charged proteins are ...