Now showing items 1-8 of 8

    • Epidemiology and risk factors for Staphylococcus aureus colonization in children in the post-PCV7 era 

      Lee, Grace; Huang, Susan Jen; Rifas-Shiman, Sheryl Lynn; Hinrichsen, Virginia; Pelton, Stephen I; Kleinman, Kenneth Paul; Hanage, William P.; Lipsitch, Marc; McAdam, Alexander John; Finkelstein, Jonathan Arie (Springer Science + Business Media, 2009)
      BACKGROUND: The incidence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) has risen dramatically in the U.S., particularly among children. Although Streptococcus pneumoniae colonization has been ...
    • A Multisite Randomized Trial of the Effects of Physician Education and Organizational Change in Chronic-Asthma Care 

      Lozano, Paula; Finkelstein, Jonathan Arie; Carey, Vincent James; Wagner, Edward W.; Inui, Thomas S.; Fuhlbrigge, Anne Louise; Soumerai, Stephen Bertram; Sullivan, Sean D.; Weiss, Scott Tillman; Weiss, Kevin (American Medical Association (AMA), 2004)
      Background Traditional primary care practice change approaches have not led to full implementation of national asthma guidelines. Objective To evaluate the effectiveness of 2 asthma care improvement strategies in ...
    • PEDSnet: a National Pediatric Learning Health System 

      Forrest, Christopher B; Margolis, Peter A; Bailey, L Charles; Marsolo, Keith; Del Beccaro, Mark A; Finkelstein, Jonathan A; Milov, David E; Vieland, Veronica J; Wolf, Bryan A; Yu, Feliciano B; Kahn, Michael G (BMJ Publishing Group, 2014)
      A learning health system (LHS) integrates research done in routine care settings, structured data capture during every encounter, and quality improvement processes to rapidly implement advances in new knowledge, all with ...
    • Population genomic datasets describing the post-vaccine evolutionary epidemiology of Streptococcus pneumoniae 

      Croucher, Nicholas J.; Finkelstein, Jonathan A.; Pelton, Stephen I.; Parkhill, Julian; Bentley, Stephen D.; Lipsitch, Marc; Hanage, William P. (Nature Publishing Group, 2015)
      Streptococcus pneumoniae is common nasopharyngeal commensal bacterium and important human pathogen. Vaccines against a subset of pneumococcal antigenic diversity have reduced rates of disease, without changing the frequency ...
    • Population genomics of post-vaccine changes in pneumococcal epidemiology 

      Croucher, Nicholas J.; Finkelstein, Jonathan A.; Pelton, Stephen I.; Mitchell, Patrick K.; Lee, Grace M.; Parkhill, Julian; Bentley, Stephen D.; Hanage, William P.; Lipsitch, Marc (2013)
      Whole genome sequencing of 616 asymptomatically carried pneumococci was used to study the impact of the 7-valent pneumococcal conjugate vaccine. Comparison of closely related isolates revealed the role of transformation ...
    • Selective and Genetic Constraints on Pneumococcal Serotype Switching 

      Croucher, Nicholas J.; Kagedan, Lisa; Thompson, Claudette M.; Parkhill, Julian; Bentley, Stephen D.; Finkelstein, Jonathan A.; Lipsitch, Marc; Hanage, William P. (Public Library of Science, 2015)
      Streptococcus pneumoniae isolates typically express one of over 90 immunologically distinguishable polysaccharide capsules (serotypes), which can be classified into “serogroups” based on cross-reactivity with certain ...
    • Stability of the pneumococcal population structure in Massachusetts as PCV13 was introduced 

      Chang, Qiuzhi; Stevenson, Abbie E; Croucher, Nicholas J; Lee, Grace M; Pelton, Stephen I; Lipsitch, Marc; Finkelstein, Jonathan A; Hanage, William P (BioMed Central, 2015)
      Background: The success of 7-valent pneumococcal conjugate vaccination (PCV-7) introduced to the US childhood immunization schedule in 2000 was partially offset by increases in invasive pneumococcal disease (IPD) and ...
    • Transition experiences and health care utilization among young adults with type 1 diabetes 

      Garvey, Katharine C; Finkelstein, Jonathan A; Laffel, Lori M; Ochoa, Victoria; Wolfsdorf, Joseph I; Rhodes, Erinn T (Dove Medical Press, 2013)
      Background: The purpose of this study was to describe the current status of adult diabetes care in young adults with type 1 diabetes and examine associations between health care transition experiences and care utilization. ...