Browsing by Author "Ma, Siming"

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    • Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii 

      Seim, Inge; Fang, Xiaodong; Xiong, Zhiqiang; Lobanov, Alexey V.; Huang, Zhiyong; Ma, Siming; Feng, Yue; Turanov, Anton A.; Zhu, Yabing; Lenz, Tobias L.; Gerashchenko, Maxim V.; Fan, Dingding; Hee Yim, Sun; Yao, Xiaoming; Jordan, Daniel; Xiong, Yingqi; Ma, Yong; Lyapunov, Andrey N.; Chen, Guanxing; Kulakova, Oksana I.; Sun, Yudong; Lee, Sang-Goo; Bronson, Roderick T.; Moskalev, Alexey A.; Sunyaev, Shamil R.; Zhang, Guojie; Krogh, Anders; Wang, Jun; Gladyshev, Vadim N. (Nature Pub. Group, 2013)
      Bats account for one-fifth of mammalian species, are the only mammals with powered flight, and are among the few animals that echolocate. The insect-eating Brandt’s bat (Myotis brandtii) is the longest-lived bat species ...

    • Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status 

      Lee, Byung Cheon; Kaya, Alaattin; Ma, Siming; Kim, Gwansu; Gerashchenko, Maxim V.; Yim, Sun Hee; Hu, Zhen; Harshman, Lawrence G.; Gladyshev, Vadim N. (2014)
      Reduced methionine (Met) intake can extend lifespan of rodents, but whether this regimen represents a general strategy for regulating aging has been controversial. Here we report that Met restriction extends lifespan in ...

    • Molecular Patterns and Signatures of Longevity 

      Ma, Siming (2016-05-02)
      Since their divergence from a common ancestor some 200 million years ago, mammals have undergone significant diversification in physiology, morphology, habitat, size, and longevity. The maximum lifespan of mammalian species ...

    • The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal 

      Seim, Inge; Ma, Siming; Zhou, Xuming; Gerashchenko, Maxim V.; Lee, Sang-Goo; Suydam, Robert; George, John C.; Bickham, John W.; Gladyshev, Vadim N. (Impact Journals LLC, 2014)
      Mammals vary dramatically in lifespan, by at least two-orders of magnitude, but the molecular basis for this difference remains largely unknown. The bowhead whale Balaena mysticetus is the longest-lived mammal known, with ...