Now showing items 1-2 of 2

    • An Analysis of the Role of the Indigenous Microbiota in Cholesterol Gallstone Pathogenesis 

      Fremont-Rahl, Jacqueline J.; Ge, Zhongming; Umana, Carlos; Whary, Mark T.; Taylor, Nancy S.; Muthupalani, Sureshkumar; Carey, Martin C.; Fox, James G.; Maurer, Kirk J. (Public Library of Science, 2013)
      Background and Aims Cholesterol gallstone disease is a complex process involving both genetic and environmental variables. No information exists regarding what role if any the indigenous gastrointestinal microbiota may ...
    • Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner 

      Calvo, Jennifer A.; Allocca, Mariacarmela; Fake, Kimberly R.; Muthupalani, Sureshkumar; Corrigan, Joshua J.; Bronson, Roderick T.; Samson, Leona D. (Impact Journals LLC, 2016)
      Nephrotoxicity is a common toxic side-effect of chemotherapeutic alkylating agents. Although the base excision repair (BER) pathway is essential in repairing DNA alkylation damage, under certain conditions the initiation ...