Now showing items 1-3 of 3

    • Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy 

      Kim, Leo A.; Wong, Lindsay L.; Amarnani, Dhanesh S.; Bigger-Allen, Alexander A.; Hu, Yang; Marko, Christina K.; Eliott, Dean; Shah, Vinay A.; McGuone, Declan; Stemmer-Rachamimov, Anat O.; Gai, Xiaowu; D’Amore, Patricia A.; Arboleda-Velasquez, Joseph F. (Molecular Vision, 2015)
      Purpose Epiretinal fibrovascular membranes (FVMs) are a hallmark of proliferative diabetic retinopathy (PDR). Surgical removal of FVMs is often indicated to treat tractional retinal detachment. This potentially informative ...
    • Conversion to aflibercept for diabetic macular edema unresponsive to ranibizumab or bevacizumab 

      Lim, Laurence S; Ng, Wei Yan; Mathur, Ranjana; Wong, Doric; Wong, Edmund YM; Yeo, Ian; Cheung, Chui Ming Gemmy; Lee, Shu Yen; Wong, Tien Yin; Papakostas, Thanos D; Kim, Leo A (Dove Medical Press, 2015)
      Background: The purpose of this study was to determine if eyes with diabetic macular edema (DME) unresponsive to ranibizumab or bevacizumab would benefit from conversion to aflibercept. Methods: This study was conducted ...
    • Tamoxifen Toxicity in Cultured Retinal Pigment Epithelial Cells Is Mediated by Concurrent Regulated Cell Death Mechanisms 

      Kim, Leo Am; Amarnani, Dhanesh; Gnanaguru, Gopalan; Tseng, Wen Allen; Vavvas, Demetrios; D'Amore, Patricia Ann (Association for Research in Vision and Ophthalmology (ARVO), 2014)
      Purpose.: To evaluate the mechanism of tamoxifen-induced cell death in human cultured RPE cells, and to investigate concurrent cell death mechanisms including pyroptosis, apoptosis, and necroptosis. Methods.: Human RPE ...