Now showing items 1-3 of 3

    • Evidence of Molecular Evolution Driven by Recombination Events Influencing Tropism in a Novel Human Adenovirus that Causes Epidemic Keratoconjunctivitis 

      Walsh, Michael P.; Chintakuntlawar, Ashish; Harrach, Balázs; Hudson, Nolan R.; Schnurr, David; Heim, Albert; Seto, Donald; Jones, Morris S.; Robinson, Christopher; Madisch, Ijad; Chodosh, James (Public Library of Science, 2009)
      In 2005, a human adenovirus strain (formerly known as HAdV-D22/H8 but renamed here HAdV-D53) was isolated from an outbreak of epidemic keratoconjunctititis (EKC), a disease that is usually caused by HAdV-D8, -D19, or -D37, ...
    • Molecular evolution of human adenoviruses 

      Robinson, Christopher; Singh, Gurdeep; Lee, Jeong Yoon; Dehghan, Shoaleh; Rajaiya, Jaya; Liu, Elizabeth B.; Yousuf, Mohammad Abu; Betensky, Rebecca Aubrey; Jones, Morris S.; Dyer, David W.; Seto, Donald; Chodosh, James (Nature Publishing Group, 2013)
      The recent emergence of highly virulent human adenoviruses (HAdVs) with new tissue tropisms underscores the need to determine their ontogeny. Here we report complete high quality genome sequences and analyses for all the ...
    • Predicting the Next Eye Pathogen: Analysis of a Novel Adenovirus 

      Robinson, Christopher; Zhou, Xiaohong; Rajaiya, Jayabarathy; Yousuf, Mohammad Abu; Singh, Gurdeep; DeSerres, Joshua J.; Walsh, Michael P.; Wong, Sallene; Seto, Donald; Dyer, David W.; Chodosh, James; Jones, Morris S. (American Society of Microbiology, 2013)
      For DNA viruses, genetic recombination, addition, and deletion represent important evolutionary mechanisms. Since these genetic alterations can lead to new, possibly severe pathogens, we applied a systems biology approach ...