Now showing items 1-5 of 5

    • Antiretroviral Regimens in Pregnancy and Breast-Feeding in Botswana 

      Shapiro, R.L.; Hughes, M.D.; Ogwu, Anthony; Kitch, Doug William; Lockman, Shahin; Moffat, C.; Makhema, Joseph Moeketsi; Moyo, S; Thior, Ibou; McIntosh, Kenneth; van Widenfelt, E.; Leidner, Jean A.; Powis, Kathleen Marie; Asmelash, A.; Tumbare, E.; Zwerski, S.; Sharma, Upasna; Handelsman, E.; Mburu, K.; Jayeoba, O.; Moko, E.; Souda, Shashidhar Vaman; Lubega, E.; Akhtar, M.; Wester, C William; Tuomola, R.; Snowden, W.; Martinez-Tristani, M.; Mazhani, L.; Essex, Myron Elmer (New England Journal of Medicine (NEJM/MMS), 2010)
      BACKGROUND: The most effective highly active antiretroviral therapy (HAART) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) in pregnancy and its efficacy during breast-feeding are ...
    • Cotrimoxazole Prophylaxis and Risk of Severe Anemia or Severe Neutropenia in HAART-Exposed, HIV-Uninfected Infants 

      Dryden-Peterson, Scott; Jayeoba, Oluwemimo; Hughes, Michael D.; Jibril, Haruna; McIntosh, Kenneth; Modise, Taolo A.; Asmelash, Aida; Powis, Kathleen M.; Essex, Max; Shapiro, Roger L.; Lockman, Shahin (Public Library of Science, 2013)
      Background: Prophylactic cotrimoxazole is recommended for infants born to HIV-infected mothers. However, cotrimoxazole may increase the risk of severe anemia or neutropenia. Methods: We compared the proportion of HIV-exposed ...
    • High Prevalence of Hypertension and Placental Insufficiency, but No In Utero HIV Transmission, among Women on HAART with Stillbirths in Botswana 

      Souda, Sajini; Parekh, Natasha; Binda, Kelebogile; Kayembe, Mukendi; Svab, Petr; Babitseng, Orphinah; Jimbo, William; Creek, Tracy; Essex, Max; Shapiro, Roger L.; Lockman, Shahin; Powis, Kathleen Marie; Makhema, Joseph Moeketsi; Roberts, Drucilla Jane (Public Library of Science, 2012)
      Background: Increased stillbirth rates occur among HIV-infected women, but no studies have evaluated the pathological basis for this increase, or whether highly active antiretroviral therapy (HAART) influences the etiology ...
    • HIV-exposed children account for more than half of 24-month mortality in Botswana 

      Zash, Rebecca; Souda, Sajini; Leidner, Jean; Ribaudo, Heather; Binda, Kelebogile; Moyo, Sikhulile; Powis, Kathleen M.; Petlo, Chipo; Mmalane, Mompati; Makhema, Joe; Essex, Max; Lockman, Shahin; Shapiro, Roger (BioMed Central, 2016)
      Background: The contribution of HIV-exposure to childhood mortality in a setting with widespread antiretroviral treatment (ART) availability has not been determined. Methods: From January 2012 to March 2013, mothers were ...
    • Vitamin D Insufficiency in HIV-infected Pregnant Women Receiving Antiretroviral Therapy is Not Associated With Morbidity, Mortality or Growth Impairment in Their Uninfected Infants in Botswana 

      Powis, Kathleen Marie; Lockman, Shahin; Smeaton, Laura Marie; Hughes, Michael David; Fawzi, Wafaie W.; Ogwu, Anthony; Moyo, Sikhulile; van Widenfelt, Erik; von Oettingen, Julia Elisabeth; Makhema, Joseph; Essex, Max; Shapiro, Roger L. (Ovid Technologies (Wolters Kluwer Health), 2014)
      Background Low maternal 25(OH)D (vitamin D) values have been associated with higher mortality and impaired growth among HIV-exposed uninfected (HEU) infants of antiretroviral (ART)-naïve women. These associations have ...