Now showing items 1-6 of 6

    • Cloud-Enabled Microscopy and Droplet Microfluidic Platform for Specific Detection of Escherichia coli in Water 

      Golberg, Alexander; Linshiz, Gregory; Kravets, Ilia; Stawski, Nina; Hillson, Nathan J.; Yarmush, Martin L.; Marks, Robert S.; Konry, Tania (Public Library of Science, 2014)
      We report an all-in-one platform – ScanDrop – for the rapid and specific capture, detection, and identification of bacteria in drinking water. The ScanDrop platform integrates droplet microfluidics, a portable imaging ...
    • Eradication of Multidrug-Resistant Pseudomonas Biofilm With Pulsed Electric Fields 

      Khan, Saiqa I.; Blumrosen, Gaddi; Vecchio, Daniela; Golberg, Alexander; Hamblin, Michael; McCormack, Michael; Yarmush, Martin; Austen, William (Wiley, 2015-09-09)
      Biofilm formation is a significant problem, accounting for over eighty percent of microbial infections in the body. Biofilm eradication is problematic due to increased resistance to antibiotics and antimicrobials as compared ...
    • Live single cell functional phenotyping in droplet nano-liter reactors 

      Konry, Tania; Golberg, Alexander; Yarmush, Martin (Nature Publishing Group, 2013)
      While single cell heterogeneity is present in all biological systems, most studies cannot address it due to technical limitations. Here we describe a nano-liter droplet microfluidic-based approach for stimulation and ...
    • The Role of CHI3L1 (Chitinase-3-Like-1) in the Pathogenesis of Infections in Burns in a Mouse Model 

      Bohr, Stefan; Patel, Suraj J.; Vasko, Radovan; Shen, Keyue; Golberg, Alexander; Berthiaume, Francois; Yarmush, Martin L. (Public Library of Science, 2015)
      In severe burn injury the unique setting of a depleted, dysfunctional immune system along with a loss of barrier function commonly results in opportunistic infections that eventually proof fatal. Unfortunately, the dynamic ...
    • Skin Rejuvenation with Non-Invasive Pulsed Electric Fields 

      Golberg, Alexander; Khan, Saiqa; Belov, Vasily; Quinn, Kyle P.; Albadawi, Hassan; Felix Broelsch, G.; Watkins, Michael T.; Georgakoudi, Irene; Papisov, Mikhail; Mihm Jr., Martin C.; Austen Jr., William G.; Yarmush, Martin L. (Nature Publishing Group, 2015)
      Degenerative skin diseases affect one third of individuals over the age of sixty. Current therapies use various physical and chemical methods to rejuvenate skin; but since the therapies affect many tissue components including ...
    • Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks” 

      Golberg, Alexander; Bruinsma, Bote G.; Uygun, Basak E.; Yarmush, Martin L. (Nature Publishing Group, 2015)
      Irreversible electroporation (IRE) is an emerging, minimally invasive technique for solid tumors ablation, under clinical investigation for cancer therapy. IRE affects only the cell membrane, killing cells while preserving ...