Browsing by Author "Muzumdar, Mandar Deepak"

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    • Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers 

      Muzumdar, Mandar Deepak; Dorans, Kimberly Judith; Chung, Katherine Minjee; Robbins, Rebecca; Tammela, Tuomas; Gocheva, Vasilena; Li, Carman Man-Chung; Jacks, Tyler (Nature Publishing Group, 2016)
      Although it has become increasingly clear that cancers display extensive cellular heterogeneity, the spatial growth dynamics of genetically distinct clones within developing solid tumours remain poorly understood. Here we ...