Now showing items 1-3 of 3

    • Comparative Analysis of the Transcriptome Across Distant Species 

      Gerstein, Mark B.; Rozowsky, Joel; Yan, Koon-Kiu; Wang, Daifeng; Cheng, Chao; Brown, James B.; Davis, Carrie A.; Hillier, LaDeana; Sisu, Cristina; Li, Jingyi Jessica; Pei, Baikang; Harmanci, Arif O.; Duff, Michael O.; Djebali, Sarah; Alexander, Roger P.; Alver, Burak; Auerbach, Raymond; Bell, Kimberly; Bickel, Peter J.; Boeck, Max E.; Boley, Nathan P.; Booth, Benjamin W.; Cherbas, Lucy; Cherbas, Peter; Di, Chao; Dobin, Alex; Drenkow, Jorg; Ewing, Brent; Fang, Gang; Fastuca, Megan; Feingold, Elise A.; Frankish, Adam; Gao, Guanjun; Good, Peter J.; Guigó, Roderic; Hammonds, Ann; Harrow, Jen; Hoskins, Roger A.; Howald, Cédric; Hu, Long; Huang, Haiyan; Hubbard, Tim J. P.; Huynh, Chau; Jha, Sonali; Kasper, Dionna; Kato, Masaomi; Kaufman, Thomas C.; Kitchen, Robert R.; Ladewig, Erik; Lagarde, Julien; Lai, Eric; Leng, Jing; Lu, Zhi; MacCoss, Michael; May, Gemma; McWhirter, Rebecca; Merrihew, Gennifer; Miller, David M.; Mortazavi, Ali; Murad, Rabi; Oliver, Brian; Olson, Sara; Park, Peter; Pazin, Michael J.; Perrimon, Norbert; Pervouchine, Dmitri; Reinke, Valerie; Reymond, Alexandre; Robinson, Garrett; Samsonova, Anastasia; Saunders, Gary I.; Schlesinger, Felix; Sethi, Anurag; Slack, Frank J.; Spencer, William C.; Stoiber, Marcus H.; Strasbourger, Pnina; Tanzer, Andrea; Thompson, Owen A.; Wan, Kenneth H.; Wang, Guilin; Wang, Huaien; Watkins, Kathie L.; Wen, Jiayu; Wen, Kejia; Xue, Chenghai; Yang, Li; Yip, Kevin; Zaleski, Chris; Zhang, Yan; Zheng, Henry; Brenner, Steven E.; Graveley, Brenton R.; Celniker, Susan E.; Gingeras, Thomas R.; Waterston, Robert (Springer Science and Business Media LLC, 2014-08-27)
      The transcriptome is the readout of the genome. Identifying common features in it across distant species can reveal fundamental principles. To this end, the ENCODE and modENCODE consortia have generated large amounts of ...
    • Deep Annotation of Drosophila melanogaster microRNAs Yields Insights Into Their Processing, Modification, and Emergence 

      Berezikov, Eugene; Robine, Nicolas; Samsonova, Anastasia; Westholm, Jakub O.; Navqi, Ammar; Hung, Jui-Hung; Okamura, Katsutomo; Dai, Qi; Bortolamiol-Becet, Diane; Martin, Raquel; Zhao, Yongjun; Zamore, Phillip D.; Hannon, Gregory J.; Marra, Marco A.; Weng, Zhiping; Perrimon, Norbert; Lai, Eric C. (Cold Spring Harbor Laboratory, 2011-02)
      Since the initial annotation of miRNAs from cloned short RNAs by the Ambros, Tuschl, and Bartel groups in 2001, more than a hundred studies have sought to identify additional miRNAs in various species. We report here a ...
    • False Negative Rates in Drosophila Cell-Based RNAi Screens: A Case Study 

      Booker, Matthew; Samsonova, Anastasia; Kwon, Young; Flockhart, Ian; Mohr, Stephanie; Perrimon, Norbert (Springer Science and Business Media LLC, 2011-01-20)
      Background High-throughput screening using RNAi is a powerful gene discovery method but is often complicated by false positive and false negative results. Whereas false positive results associated with RNAi reagents has ...