Browsing by Author "Moslehi, Javid"

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    • Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging 

      Gomes, Ana P.; Price, Nathan L.; Ling, Alvin J.Y.; Moslehi, Javid; Montgomery, Magdalene K.; Rajman, Luis; White, James Patrick; Teodoro, João S.; Wrann, Christiane Dorothea; Hubbard, Basil P.; Mercken, Evi M.; Palmeira, Carlos M.; de Cabo, Rafael; Rolo, Anabela P.; Turner, Nigel; Bell, Eric L.; Sinclair, David Andrew (Elsevier BV, 2013)
      Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation ...