Browsing by Author "Delahanty, Linda"
Now showing items 1-9 of 9
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Depression, Stress and Weight Loss in Individuals with Metabolic Syndrome in SHINE, a DPP Translation Study
Trief, Paula M.; Cibula, Donald; Delahanty, Linda M.; Weinstock, Ruth S. (2014)OBJECTIVE To examine the relationships between elevated depression symptoms (EDS) or stress and weight loss in SHINE, a telephonic, primary-care based, translation of the Diabetes Prevention Program. DESIGN AND METHODS ... -
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: the Diabetes Prevention Program
Pollin, Toni I.; Isakova, Tamara; Jablonski, Kathleen A.; de Bakker, Paul I. W.; Taylor, Andrew; McAteer, Jarred; Pan, Qing; Horton, Edward S.; Delahanty, Linda M.; Altshuler, David; Shuldiner, Alan R.; Goldberg, Ronald B.; Florez, Jose Carlos; Franks, Paul W. (Public Library of Science, 2012)Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 ... -
Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification, Metformin Treatment, or Standard Care in the Diabetes Prevention Program
Delahanty, Linda Michele; Pan, Qing; Jablonski, Kathleen A.; Watson, Karol E.; McCaffery, Jeanne M.; Shuldiner, Alan; Kahn, Steven E.; Knowler, William C.; Florez, Jose Carlos; Franks, Paul W. (American Diabetes Association, 2012)OBJECTIVE: We tested genetic associations with weight loss and weight regain in the Diabetes Prevention Program, a randomized controlled trial of weight loss–inducing interventions (lifestyle and metformin) versus placebo. ... -
Perceived Impact of Diabetes Genetic Risk Testing Among Patients at High Phenotypic Risk for Type 2 Diabetes
Markowitz, Sarah M.; Park, Elyse Richelle; Delahanty, Linda Michele; O’Brien, Kelsey E.; Grant, Richard W. (American Diabetes Association, 2011)Objective: Rapid advances in diabetes genetic epidemiology may lead to a new era of “personalized medicine” based on individual genetic risk assessment. There is minimal experience to guide how best to clinically implement ... -
Personalized Genetic Risk Counseling to Motivate Diabetes Prevention: A randomized trial
Grant, Richard W.; O’Brien, Kelsey E.; Waxler, Jessica L.; Vassy, Jason L.; Delahanty, Linda M.; Bissett, Laurie G.; Green, Robert C.; Stember, Katherine G.; Guiducci, Candace; Park, Elyse R.; Florez, Jose C.; Meigs, James B. (American Diabetes Association, 2013)OBJECTIVE To examine whether diabetes genetic risk testing and counseling can improve diabetes prevention behaviors. RESEARCH DESIGN AND METHODS We conducted a randomized trial of diabetes genetic risk counseling among ... -
Pretreatment, Psychological, and Behavioral Predictors of Weight Outcomes Among Lifestyle Intervention Participants in the Diabetes Prevention Program (DPP)
Delahanty, Linda M.; Peyrot, Mark; Shrader, Peter J.; Williamson, Donald A.; Meigs, James B.; Nathan, David M. (American Diabetes Association, 2013)OBJECTIVE To identify the most important pretreatment characteristics and changes in psychological and behavioral factors that predict weight outcomes in the Diabetes Prevention Program (DPP). RESEARCH DESIGN AND METHODS ... -
A Randomized Controlled Trial of Cognitive Behavioral Therapy for Adherence and Depression (CBT-AD) in Patients With Uncontrolled Type 2 Diabetes
Safren, Steven A.; Gonzalez, Jeffrey S.; Wexler, Deborah J.; Psaros, Christina; Delahanty, Linda M.; Blashill, Aaron J.; Margolina, Aleksandra I.; Cagliero, Enrico (American Diabetes Association, 2014)OBJECTIVE To test cognitive behavioral therapy for adherence and depression (CBT-AD) in type 2 diabetes. We hypothesized that CBT-AD would improve adherence; depression; and, secondarily, hemoglobin A1c (A1C). RESEARCH ... -
Short and long-term lifestyle coaching approaches used to address diverse participant barriers to weight loss and physical activity adherence
Venditti, Elizabeth M; Wylie-Rosett, Judith; Delahanty, Linda M; Mele, Lisa; Hoskin, Mary A; Edelstein, Sharon L (BioMed Central, 2014)Background: Individual barriers to weight loss and physical activity goals in the Diabetes Prevention Program, a randomized trial with 3.2 years average treatment duration, have not been previously reported. Evaluating ... -
Validity of Medication Adherence Self-Reports in Adults With Type 2 Diabetes
Gonzalez, Jeffrey S.; Schneider, Havah E.; Wexler, Deborah J.; Psaros, Christina; Delahanty, Linda M.; Cagliero, Enrico; Safren, Steven A. (American Diabetes Association, 2013)OBJECTIVE To assess the validity of self-report measures of diabetes medication adherence and evaluate the effect of depression on the validity of these reports. RESEARCH DESIGN AND METHODS Adults with type 2 diabetes, ...