Browsing by Author "Khan, Liakot"

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Intracellular lumen extension requires ERM-1-dependent apical membrane expansion and AQP-8-mediated flux

Khan, Liakot A.; Zhang, Hongjie; Abraham, Nessy; Sun, Lei; Fleming, John T.; Buechner, Matthew; Hall, David H.; Gobel, Verena (2013)

SUMMARY Many unicellular tubes such as capillaries form lumens intracellularly, a process that is not well understood. Here we show that the cortical membrane organizer ERM-1 is required to expand the intracellular ...
Vesicular sorting controls the polarity of expanding membranes in the C. elegans intestine

Zhang, Hongjie; Kim, Ahlee; Abraham, Nessy; Khan, Liakot A.; Göbel, Verena (Landes Bioscience, 2013)

Biological tubes consist of polarized epithelial cells with apical membranes building the central lumen and basolateral membranes contacting adjacent cells or the extracellular matrix. Cellular polarity requires distinct ...