Browsing by Author "Gershow, Marc"

Now showing items 1-10 of 10

    • Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons 

      Luo, Linjiao; Cook, N.; Venkatachalam, Vivek; Martinez-Velazquez, L. A.; Zhang, Xiaosong; Calvo, A. C.; Hawk, J.; Macinnis, Bronwyn Lee; Frank, Michelle Murrah; Ng, J. H. R.; Klein, Mason Joseph; Gershow, M; Hammarlund, M.; Goodman, M. B.; Colon-Ramos, D. A.; Zhang, Y.; Samuel, Aravinthan DT (Proceedings of the National Academy of Sciences, 2014)
      The nematode Caenorhabditis elegans navigates toward a preferred temperature setpoint (Ts) determined by long-term temperature exposure. During thermotaxis, the worm migrates down temperature gradients at temperatures above ...

    • Controlling Airborne Cues to Study Small Animal Navigation 

      Gershow, Marc; Berck, Matthew E; Mathew, Dennis; Luo, Linjiao; Kane, Elizabeth Anne; Carlson, John R; Samuel, Aravinthan DT (Nature Publishing Group, 2012)
      Small animals such as nematodes and insects analyze airborne chemical cues to infer the direction of favorable and noxious locations. In these animals, the study of navigational behavior evoked by airborne cues has been ...

    • Detecting Single Stranded DNA with a Solid State Nanopore 

      Fologea, Daniel; Gershow, Marc; Ledden, Bradley; McNabb, David S.; Golovchenko, Jene Andrew; Li, Jiali (American Chemical Society (ACS), 2005)
      Voltage biased solid-state nanopores are used to detect and characterize individual single stranded DNA molecules of fixed micrometer length by operating a nanopore detector at pH values greater than ∼11.6. The distribution ...

    • DNA molecules and configurations in a solid-state nanopore microscope 

      Li, Jiali; Gershow, Marc; Stein, Derek; Brandin, Eric Richard; Golovchenko, Jene Andrew (Nature Publishing Group, 2003)
      A nanometre scale pore in a solid state membrane provides a new way to electronically probe the structure of single linear polymers, including those of biological interest in their native environments. Previous work with ...

    • Functional diversity among sensory receptors in a Drosophila olfactory circuit 

      Mathew, Dennis; Martelli, Carlotta; Kelley-Swift, Elizabeth; Brusalis, Christopher; Gershow, Marc; Samuel, Aravinthan DT; Emonet, Thierry; Carlson, John R. (Proceedings of the National Academy of Sciences, 2013)
      The ability of an animal to detect, discriminate, and respond to odors depends on the function of its olfactory receptor neurons (ORNs), which in turn depends ultimately on odorant receptors. To understand the diverse ...

    • Navigational Decision Making in Drosophila Thermotaxis 

      Luo, Linjiao; Gershow, Marc Herman; Rosenzweig, Mark; Kang, Kyeonglin; Fang-Yen, Christopher M.; Garrity, Paul A,; Samuel, Aravinthan DT (Society for Neuroscience, 2010)
      A mechanistic understanding of animal navigation requires quantitative assessment of the sensorimotor strategies used during navigation and quantitative assessment of how these strategies are regulated by cellular sensors. ...

    • Proprioceptive Coupling within Motor Neurons Drives C. Elegans Forward Locomotion 

      Wen, Quan; Po, Michelle D.; Hulme, Elizabeth; Chen, Sway; Liu, Xinyu; Kwok, Sen Wai; Gershow, Marc; Leifer, Andrew M.; Butler, Victoria; Fang-Yen, Christopher; Kawano, Taizo; Schafer, William R.; Whitesides, George M.; Wyart, Matthieu; Chklovskii, Dmitri B.; Zhen, Mei; Samuel, Aravinthan DT (Elsevier BV, 2012)
      Locomotion requires coordinated motor activity throughout an animal’s body. In both vertebrates and invertebrates, chains of coupled central pattern generators (CPGs) are commonly evoked to explain local rhythmic behaviors. ...

    • Recapturing and trapping single molecules with a solid-state nanopore 

      Gershow, Marc; Golovchenko, Jene Andrew (Nature Publishing Group, 2007)
      The development of solid state nanopores, inspired by their biological counterparts, shows great potential for the study of single macromolecules. Applications such as DNA sequencing and exploration of protein folding will ...

    • Sensorimotor structure of Drosophila larva phototaxis 

      Kane, E. A.; Gershow, M; Afonso, Bruno; Larderet, I.; Klein, Mason Joseph; Carter, A. R.; de Bivort, Benjamin Lovegren; Sprecher, S. G.; Samuel, Aravinthan DT (Proceedings of the National Academy of Sciences, 2013)
      The avoidance of light by fly larvae is a classic paradigm for sensorimotor behavior. Here, we use behavioral assays and video microscopy to quantify the sensorimotor structure of phototaxis using the Drosophila larva. ...

    • Sensory determinants of behavioral dynamics in Drosophila thermotaxis 

      Klein, Mason Joseph; Afonso, Bruno; Vonner, Ashley James; Hernandez-Nunez, Luis; Berck, Matthew E; Tabone, Christopher; Kane, Elizabeth Anne; Pieribone, Vincent A.; Nitabach, Michael N.; Cardona, Albert; Zlatic, Marta; Sprecher, Simon G.; Gershow, Marc; Garrity, Paul A.; Samuel, Aravinthan DT (Proceedings of the National Academy of Sciences, 2014)
      Complex animal behaviors are built from dynamical relationships between sensory inputs, neuronal activity, and motor outputs in patterns with strategic value. Connecting these patterns illuminates how nervous systems compute ...