Now showing items 1-4 of 4

    • Assessing modularity of developmental enhancers in Drosophila melanogaster 

      Martin, Tara Laine (2014-10-22)
      Gene expression is critical for animal development as cells divide and differentiate into multiple cell types. Cell-type specific gene expression is controlled by enhancers, DNA sequences that can direct expression of a ...
    • Dissecting Sources of Quantitative Gene Expression Pattern Divergence Between Drosophila Species 

      Eckenrode, Kelly B; Lydiard-Martin, Tara; Pearl-Waserman, Sivanne; Wunderlich, Zeba Batool; Bragdon, Meghan D.; Depace, Angela (Nature Publishing Group, 2012)
      The function of a transcriptional circuit is compared in three closely related species of Drosophila. Using quantitative imaging of gene expression, targeted transgenic reporter fly lines, and a computational framework, the ...
    • Regulation of Yolk Catabolism in Early Embryogenesis 

      Kuhn, Hallie (2015-08-19)
      Yolk provides an important source of nutrients during the early development of oviparous (non-platental) organisms. In addition to phosphate and lipids, it is com- posed mainly of vitellogenin proteins packed into ...
    • SiteOut: An Online Tool to Design Binding Site-Free DNA Sequences 

      Estrada, Javier; Ruiz-Herrero, Teresa; Scholes, Clarissa; Wunderlich, Zeba; DePace, Angela H. (Public Library of Science, 2016)
      DNA-binding proteins control many fundamental biological processes such as transcription, recombination and replication. A major goal is to decipher the role that DNA sequence plays in orchestrating the binding and activity ...