Browsing by Author "Bredella, Miriam"
Now showing items 1-11 of 11
-
Assessment of abdominal fat compartments using DXA in premenopausal women from anorexia nervosa to morbid obesity
Bredella, Miriam A.; Gill, Corey M.; Keating, Leigh K.; Torriani, Martin; Anderson, Ellen J.; Punyanitya, Mark; Wilson, Kevin E.; Kelly, Thomas L.; Miller, Karen K. (2013)Objective: The purpose of this study was to test a newly developed DXA method for abdominal fat depot quantification in subjects with AN, normal weight, and obesity using CT as a gold standard. Design and Methods 135 ... -
Comparing Outcomes of Two Types of Bariatric Surgery in an Adolescent Obese Population: Roux-en-Y Gastric Bypass vs. Sleeve Gastrectomy
Maffazioli, Giovana D.; Stanford, Fatima Cody; Campoverde Reyes, Karen J.; Stanley, Takara L.; Singhal, Vibha; Corey, Kathleen E.; Pratt, Janey S.; Bredella, Miriam A.; Misra, Madhusmita (Frontiers Media S.A., 2016)Background: Obesity is prevalent among adolescents and is associated with serious health consequences. Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) are bariatric procedures that cause significant weight loss ... -
Distinguishing Untreated Osteoblastic Metastases From Enostoses Using CT Attenuation Measurements
Ulano, Adam; Bredella, Miriam A.; Burke, Patrick J; Chebib, Ivan Adel; Simeone, Frank J; Huang, Ambrose J.; Torriani, Martin P.; Chang, Connie Y. (American Roentgen Ray Society, 2016)Purpose: To determine if CT density thresholds of osteoblastic bone lesions can be used to distinguish untreated osteoblastic metastases from enostoses. Materials and Methods: The study group comprised 62 patients (37 ... -
Effects of recombinant human growth hormone (rhGH) administration on body composition and cardiovascular risk factors in obese adolescent girls
Slattery, Meghan; Bredella, Miriam A; Stanley, Takara; Torriani, Martin; Misra, Madhusmita (BioMed Central, 2014)Background: Obesity is associated with a relative deficiency of growth hormone, which is predictive of greater visceral fat and markers of cardiovascular risk. The study’s purpose was to use recombinant human growth hormone ... -
Magnetic Resonance Imaging of the Elbow: A Structured Approach
Sampath, Srinath C.; Sampath, Srihari C.; Bredella, Miriam A. (SAGE Publications, 2013)Context: The elbow is a complex joint and commonly injured in athletes. Evaluation of the elbow by magnetic resonance imaging (MRI) is an important adjunct to the physical examination. To facilitate accurate diagnosis, a ... -
Plasma S100β is not a useful biomarker for tumor burden in neurofibromatosis
Smith, Miriam J.; Esparza, Sonia; Merker, Vanessa; Muzikansky, Alona; Bredella, Miriam A.; Harris, Gordon J.; Kassarjian, Ara; Cai, Wenli; Walker, James Anthony; Mautner, Victor F.; Plotkin, Scott Randall (Elsevier BV, 2013)Objectives Neurofibromatosis 1 (NF1), NF2, and schwannomatosis are characterized by a predisposition to develop multiple neurofibromas and schwannomas. Currently, there is no blood test to estimate tumor burden in ... -
Quantitative Assessment of Whole-Body Tumor Burden in Adult Patients with Neurofibromatosis
Plotkin, Scott Randall; Bredella, Miriam A.; Cai, Wenli; Kassarjian, Ara; Harris, Gordon J.; Esparza, Sonia; Merker, Vanessa L.; Munn, Lance Leon; Muzikansky, Alona; Askenazi, Manor; Nguyen, Rosa; Wenzel, Ralph; Mautner, Victor F. (Public Library of Science (PLoS), 2012)Purpose Patients with neurofibromatosis 1 (NF1), NF2, and schwannomatosis are at risk for multiple nerve sheath tumors and premature mortality. Traditional magnetic resonance imaging (MRI) has limited ability to assess ... -
Quantitative contrast-enhanced CT attenuation evaluation of osseous metastases following chemotherapy
Chang, Connie Y.; Simeone, Frank J; Torriani, Martin P.; Bredella, Miriam A. (Springer Nature, 2017)Purpose: Osseous metastases often undergo an osteoblastic response following chemotherapy also known as the “flare” phenomenon. The purpose of our study was to demonstrate the quantitative CT changes in density of osseous ... -
Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues
Scheller, Erica L.; Doucette, Casey R.; Learman, Brian S.; Cawthorn, William P.; Khandaker, Shaima; Schell, Benjamin; Wu, Brent; Ding, Shi-Ying; Bredella, Miriam A.; Fazeli, Pouneh K.; Khoury, Basma; Jepsen, Karl J.; Pilch, Paul F.; Klibanski, Anne; Rosen, Clifford J.; MacDougald, Ormond A. (2015)Marrow adipose tissue (MAT) accumulates in diverse clinical conditions but remains poorly understood. Here we show region-specific variation in MAT adipocyte development, regulation, size, lipid composition, gene expression, ... -
Relationship between whole-body tumor burden, clinical phenotype, and quality of life in patients with neurofibromatosis
Merker, Vanessa; Bredella, Miriam A.; Cai, Wenli; Kassarjian, Ara; Harris, Gordon J.; Muzikansky, Alona; Nguyen, Rosa; Mautner, Victor F.; Plotkin, Scott Randall (Wiley-Blackwell, 2014)Patients with neurofibromatosis 1 (NF1), NF2, and schwannomatosis share a predisposition to develop multiple nerve sheath tumors. Previous studies have demonstrated that patients with NF1 and NF2 have reduced quality of ... -
Tumor Burden in Patients with Neurofibromatosis Types 1 and 2 and Schwannomatosis: Determination on Whole-Body MR Images
Cai, Wenli; Kassarjian, Ara; Bredella, Miriam A.; Harris, Gordon J.; Yoshida, Hiroyuki; Mautner, Victor F.; Wenzel, Ralph; Plotkin, Scott Randall (Radiological Society of North America (RSNA), 2009)Purpose: To develop a three-dimensional (3D) segmentation and computerized volumetry technique for use in the assessment of neurofibromatosis and to assess the ability of this technique to aid in the calculation of tumor ...