Browsing by Author "Wain, John Charles"
Now showing items 1-3 of 3
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Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs
Mou, Hongmei; Zhao, Rui; Sherwood, Richard Irving; Ahfeldt, Tim; Lapey, Allen; Wain, John Charles; Sicilian, Leonard; Izvolsky, Konstantin; Lau, Frank; Musunuru, Kiran; Cowan, Chad A.; Rajagopal, Jayaraj (Elsevier BV, 2012)Deriving lung progenitors from patient-specific pluripotent cells is a key step in producing differentiated lung epithelium for disease modeling and transplantation. By mimicking the signaling events that occur during mouse ... -
Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer
Cleary, James M.; Mamon, Harvey J.; Szymonifka, Jackie; Bueno, Raphael; Choi, Noah; Donahue, Dean M.; Fidias, Panos M.; Gaissert, Henning A.; Jaklitsch, Michael T.; Kulke, Matthew H.; Lynch, Thomas P.; Mentzer, Steven J.; Meyerhardt, Jeffrey A.; Swanson, Richard S.; Wain, John; Fuchs, Charles S.; Enzinger, Peter C. (BioMed Central, 2016)Background: Patients with locally advanced esophageal cancer who are treated with trimodality therapy have a high recurrence rate. Preclinical evidence suggests that inhibition of cyclooxygenase 2 (COX2) increases the ... -
Pathologic Characteristics of Resected Squamous Cell Carcinoma of the Trachea: Prognostic Factors Based on an Analysis of 59 Cases
Honings, Jimmie; Gaissert, Henning Arthur; Ruangchira-Urai, Ruchira; Wain, John Charles; Wright, Cameron Dorrans; Mathisen, Douglas James; Mark, Eugene Jerome (Springer-Verlag, 2009)While squamous cell carcinoma (SCC) is the most common tracheal malignancy, few reports describe the pathologic considerations that may guide intraoperative decisions and prognostic assessment. We reviewed 59 tracheal SCC ...