Browsing by Author "Armoundas, Antonis"

Now showing items 1-4 of 4

    • Cardiac mitochondria exhibit dynamic functional clustering 

      Kurz, Felix T.; Aon, Miguel A.; O'Rourke, Brian; Armoundas, Antonis A. (Frontiers Media S.A., 2014)
      Multi-oscillatory behavior of mitochondrial inner membrane potential ΔΨm in self-organized cardiac mitochondrial networks can be triggered by metabolic or oxidative stress. Spatio-temporal analyses of cardiac mitochondrial ...

    • Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy 

      Thoonen, Robrecht; Ernande, Laura; Cheng, Juan; Nagasaka, Yasuko; Yao, Vincent; Miranda-Bezerra, Alexandre; Chen, Chan; Chao, Wei; Panagia, Marcello; Sosnovik, David E.; Puppala, Dheeraj; Armoundas, Antonis A.; Hindle, Allyson; Bloch, Kenneth; Buys, Emmanuel; Scherrer-Crosbie, Marielle (Elsevier BV, 2015)
      Brown adipose tissue (BAT) has well recognized thermogenic properties mediated by uncoupling protein 1 (UCP1); more recently, BAT has been demonstrated to modulate cardiovascular risk factors. To investigate whether BAT ...

    • Mitochondrial redox and pH signaling occurs in axonal and synaptic organelle clusters 

      Breckwoldt, Michael O.; Armoundas, Antonis A.; Aon, Miguel A.; Bendszus, Martin; O’Rourke, Brian; Schwarzländer, Markus; Dick, Tobias P.; Kurz, Felix T. (Nature Publishing Group, 2016)
      Redox switches are important mediators in neoplastic, cardiovascular and neurological disorders. We recently identified spontaneous redox signals in neurons at the single mitochondrion level where transients of glutathione ...

    • A Novel Method to Capture the Onset of Dynamic Electrocardiographic Ischemic Changes and its Implications to Arrhythmia Susceptibility 

      Sayadi, Omid; Puppala, Dheeraj; Ishaque, Nosheen; Doddamani, Rajiv; Merchant, Faisal M.; Barrett, Conor; Singh, Jagmeet P.; Heist, E. Kevin; Mela, Theofanie; Martínez, Juan Pablo; Laguna, Pablo; Armoundas, Antonis A. (Blackwell Publishing Ltd, 2014)
      Background: This study investigates the hypothesis that morphologic analysis of intracardiac electrograms provides a sensitive approach to detect acute myocardial infarction or myocardial infarction‐induced arrhythmia ...