Now showing items 1-13 of 13

    • Cavum septi pellucidi in first-episode schizophrenia and first-episode affective psychosis: an MRI study 

      Kasai, Kiyoto; McCarley, Robert William; Salisbury, Dean F.; Onitsuka, Toshiaki; Demeo, Susan; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; Shenton, Martha Elizabeth (Elsevier BV, 2004)
      A high prevalence of abnormal cavum septi pellucidi (CSP) in schizophrenia may reflect neurodevelopmental abnormalities in midline structures of the brain. The relationship, however, between abnormal CSP and clinical ...
    • Cortico-Limbic Response to Personally Challenging Emotional Stimuli After Complete Recovery from Depression 

      Hooley, Jill Miranda; Parker, Holly Ann; Gruber, Staci Ann; Rogowska, Jadwiga; Yurgelun-Todd, Deborah; Guillaumot, Julien (Elsevier, 2009)
      People vulnerable to depression are at increased risk of relapse if they live in highly critical family environments. To explore this link, we used neuroimaging methods to examine cortico-limbic responding to personal ...
    • First-Episode Schizophrenic Psychosis Differs From First-Episode Affective Psychosis and Controls in P300 Amplitude Over Left Temporal Lobe 

      Salisbury, Dean F.; Shenton, Martha Elizabeth; Sherwood, Andrea R.; Fischer, Iris A.; Yurgelun-Todd, Deborah; Tohen, Mauricio; McCarley, Robert William (American Medical Association (AMA), 1998)
      Background: Schizophrenia is associated with central (sagittal) midline reductions of the P300 cognitive event-related potential and topographic asymmetry of P300, with reduced left temporal voltage. This P300 asymmetry ...
    • Functional MRI approach to developmental methylmercury and polychlorinated biphenyl neurotoxicity 

      White, Roberta F; Palumbo, Carole L.; Yurgelun-Todd, Deborah; Heaton, Kristin J.; Weihe, Pal; Debes, Frodi; Grandjean, Philippe (Elsevier BV, 2011)
      Prenatal and early childhood exposure to methylmercury (MeHg) or polychlorinated biphenyls (PCBs) are associated with deficits in cognitive, sensory, motor and other functions measured by neurobehavioral tests. The main ...
    • Lower Left Temporal Lobe MRI Volumes in Patients With First-Episode Schizophrenia Compared With Psychotic Patients With First-Episode Affective Disorder and Normal Subjects 

      Hirayasu, Yoshio; Shenton, Martha Elizabeth; Salisbury, Dean F.; Dickey, Chandlee C.; Fischer, Iris A.; Mazzoni, Paola; Kisler, Tanya; Arakaki, Hajime; Kwon, Jun Soo; Anderson, Jane E.; Yurgelun-Todd, Deborah; Tohen, Mauricio; McCarley, Robert William (American Psychiatric Publishing, 1998)
      Objective:Magnetic resonance imaging (MRI) studies of schizophrenic patients have revealed structural brain abnormalities, with low volumes of gray matter in the left posterior superior temporal gyrus and in medial temporal ...
    • Middle and Inferior Temporal Gyrus Gray Matter Volume Abnormalities in First-Episode Schizophrenia: An MRI Study 

      Kuroki, Noriomi; Shenton, Martha Elizabeth; Salisbury, Dean; Hirayasu, Yoshio; Onitsuka, Toshiaki; Ersner-Hershfield, Hal; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (American Psychiatric Publishing, 2006)
      Objective: Magnetic resonance imaging (MRI) studies of schizophrenia reveal temporal lobe structural brain abnormalities in the superior temporal gyrus and the amygdala-hippocampal complex. However, the middle and inferior ...
    • MRI Study of Cavum Septi Pellucidi in Schizophrenia, Affective Disorder, and Schizotypal Personality Disorder 

      Kwon, Jun Soo; Shenton, Martha Elizabeth; Hirayasu, Yoshio; Salisbury, Dean F.; Fischer, Iris A.; Dickey, Chandlee C.; Yurgelun-Todd, Deborah; Tohen, Mauricio; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (American Psychiatric Publishing, 1998)
      Objective: A cavum between the septi pellucidi may reflect neurodevelopmental anomalies in midline structures of the brain. The authors examined cavum septi pellucidi in subjects with schizophrenia, affective disorder, and ...
    • Planum Temporale and Heschl Gyrus Volume Reduction in Schizophrenia 

      Hirayasu, Yoshio; McCarley, Robert William; Salisbury, Dean F.; Tanaka, Shin; Soo Kwon, Jun; Frumin, Melissa; Snyderman, Danielle; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; Shenton, Martha Elizabeth (American Medical Association, 2000)
      Background: Magnetic resonance imaging studies in schizophrenia have revealed abnormalities in temporal lobe structures, including the superior temporal gyrus. More specifically, abnormalities have been reported in the ...
    • Prefrontal Gray Matter Volume Reduction in First Episode Schizophrenia 

      Hirayasu, Y.; Tanaka, Shin; Shenton, Martha Elizabeth; Salisbury, Dean; DeSantis, Massimo A.; Levitt, James Jonathan; Wible, Cindy; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (Oxford University Press (OUP), 2001)
      Functional measures have consistently shown prefrontal abnormalities in schizophrenia. However, structural magnetic resonance imaging (MRI) findings of prefrontal volume reduction have been less consistent. In this study, ...
    • Progressive Decrease of Left Heschl Gyrus and Planum Temporale Gray Matter Volume in First-Episode Schizophrenia 

      Kasai, Kiyoto; Shenton, Martha Elizabeth; Salisbury, Dean F.; Hirayasu, Yoshio; Onitsuka, Toshiaki; Spencer, Magdalena H.; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (American Medical Association (AMA), 2003)
      Background: The Heschl gyrus and planum temporale have crucial roles in auditory perception and language processing. Our previous investigation using magnetic resonance imaging (MRI) indicated smaller gray matter volumes ...
    • Progressive Decrease of Left Superior Temporal Gyrus Gray Matter Volume in Patients With First-Episode Schizophrenia 

      Kasai, Kiyoto; Shenton, Martha Elizabeth; Salisbury, Dean F.; Hirayasu, Yoshio; Lee, Chang-Uk; Ciszewski, Aleksandra A.; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (American Psychiatric Publishing, 2003)
      Objective: Smaller temporal lobe cortical gray matter volumes, including the left superior temporal gyrus, have been reported in magnetic resonance imaging (MRI) studies of patients with chronic schizophrenia and, more ...
    • The Right-Hemisphere and Valence Hypotheses: Could They Both be Right (and Sometimes Left)? 

      Killgore, William Dale; Yurgelun-Todd, Deborah (Oxford University Press, 2007)
      The two halves of the brain are believed to play different roles in emotional processing, but the specific contribution of each hemisphere continues to be debated. The right-hemisphere hypothesis suggests that the right ...
    • Subgenual Cingulate Cortex Volume in First-Episode Psychosis 

      Hirayasu, Yoshio; Shenton, Martha Elizabeth; Salisbury, Dean F.; Soo Kwon, Jun; Wible, Cynthia Gayle; Fischer, Iris A.; Yurgelun-Todd, Deborah; Zarate, Carlos; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (American Psychiatric Publishing, 1999)
      Objective: Gray matter volume and glucose utilization have been reported to be reduced in the left subgenual cingulate of subjects with familial bipolar or unipolar depression. It is unclear whether these findings are ...