Now showing items 1-8 of 8

    • Aggressive Regimens for Multidrug-Resistant Tuberculosis Decrease All-Cause Mortality 

      Mitnick, Carole Diane; Franke, Molly Forrest; Rich, Michael Leonard; Alcantara Viru, Felix A.; Appleton, Sasha C.; Atwood, Sidney S.; Bayona, Jaime N.; Bonilla, Cesar A.; Chalco, Katiuska; Fraser, Hamish S. F.; Furin, Jennifer J.; Guerra, Dalia; Hurtado, Rocio M.; Joseph, Keith; Llaro, Karim; Mestanza, Lorena; Mukherjee, Joia S.; Muñoz, Maribel; Palacios, Eda; Sanchez, Epifanio; Seung, Kwonjune J.; Shin, Sonya S.; Sloutsky, Alexander; Tolman, Arielle W.; Becerra, Mercedes C. (Public Library of Science, 2013)
      Rationale: A better understanding of the composition of optimal treatment regimens for multidrug-resistant tuberculosis (MDR-TB) is essential for expanding universal access to effective treatment and for developing new ...
    • Comprehensive Approach to Improving Maternal Health and Achieving MDG 5: Report from the Mountains of Lesotho 

      Satti, Hind Elkheir; Motsamai, Sophie; Chetane, Palesa; Marumo, Leshoboro; Barry, Donna; Riley, Jennifer; McLaughlin, Megan Marie; Seung, Kwonjune Justin; Mukherjee, Joia Stapleton (Public Library of Science, 2012)
      Background: Although it is now widely recognized that reductions in maternal mortality and improvements in women's health cannot be achieved through simple, vertical strategies, few programs have provided successful models ...
    • Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial 

      Milstein, Meredith; Lecca, Leonid; Peloquin, Charles; Mitchison, Denis; Seung, Kwonjune; Pagano, Marcello; Coleman, David; Osso, Elna; Coit, Julia; Vargas Vasquez, Dante Elmo; Sanchez Garavito, Epifanio; Calderon, Roger; Contreras, Carmen; Davies, Geraint; Mitnick, Carole D. (BioMed Central, 2016)
      Background: Evidence has existed for decades that higher doses of rifampin may be more effective, but potentially more toxic, than standard doses used in tuberculosis treatment. Whether increased doses of rifampin could ...
    • The Growing Problem of Multidrug-Resistant Tuberculosis in North Korea 

      Seung, Kwonjune J.; Linton, Stephen W. (Public Library of Science, 2013)
      Kwonjune Seung and Stephen Linton from the non-governmental organization EugeneBell discuss the worryingly high levels of multidrug-resistant tuberculosis they have observed in North Korea's tuberculosis sanatoria. Please ...
    • Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients 

      Ahuja, Shama D.; Ashkin, David; Avendano, Monika; Banerjee, Rita; Bauer, Melissa; Bayona, Jamie N.; Becerra, Mercedes C.; Benedetti, Andrea; Burgos, Marcos; Centis, Rosella; Chan, Eward D.; Chiang, Chen-Yuan; Cox, Helen; D'Ambrosio, Lia; DeRiemer, Kathy; Dung, Nguyen Huy; Enarson, Donald; Falzon, Dennis; Flanagan, Katherine; Flood, Jennifer; Garcia-Garcia, Maria L.; Gandhi, Neel; Granich, Reuben M.; Hollm-Delgado, Maria G.; Holtz, Timothy H.; Iseman, Michael D.; Jarlsberg, Leah G.; Keshavjee, Salmaan A.; Kim, Hye-Ryoun; Koh, Won-Jung; Lancaster, Joey; Lange, Christophe; de Lange, Wiel C. M.; Leimane, Vaira; Leung, Chi Chiu; Li, Jiehui; Menzies, Dick; Migliori, Giovanni B.; Mishustin, Sergey P.; Mitnick, Carole Diane; Narita, Masa; O'Riordan, Philly; Pai, Madhukar; Palmero, Domingo; Park, Seung-kyu; Pasvol, Geoffrey; Peña, Jose; Pérez-Guzmán, Carlos; Quelapio, Maria I. D.; Ponce-de-Leon, Alfredo; Riekstina, Vija; Robert, Jerome; Royce, Sarah; Schaaf, H. Simon; Seung, Kwonjune Justin; Shah, Lena; Shim, Tae Sun; Shin, Sonya Sunhi; Shiraishi, Yuji; Sifuentes-Osornio, José; Sotgiu, Giovanni; Strand, Matthew J.; Tabarsi, Payam; Tupasi, Thelma E.; van Altena, Robert; Van der Walt, Martie; Van der Werf, Tjip S.; Vargas, Mario H.; Viiklepp, Pirett; Westenhouse, Janice; Yew, Wing Wai; Yim, Jae-Joon (Public Library of Science, 2012)
      Background: Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of ...
    • Multidrug-Resistant Tuberculosis Treatment in North Korea: Is Scale-Up Possible? 

      Seung, Kwonjune J.; Franke, Molly; Linton, Stephen W. (Public Library of Science, 2016)
      Kwonjune Seung and colleagues describe the Eugene Bell Foundation's experience of treating MDR-TB in North Korea.
    • Outcomes of Comprehensive Care for Children Empirically Treated for Multidrug-Resistant Tuberculosis in a Setting of High HIV Prevalence 

      Satti, Hind Elkheir; McLaughlin, Megan M.; Omotayo, David B.; Keshavjee, Salmaan A.; Becerra, Mercedes C.; Mukherjee, Joia Stapleton; Seung, Kwonjune Justin (Public Library of Science, 2012)
      Background: Few studies have examined outcomes for children treated for multidrug-resistant tuberculosis (MDR-TB), including those receiving concomitant treatment for MDR-TB and HIV co-infection. In Lesotho, where the adult ...
    • Outcomes of Multidrug-Resistant Tuberculosis Treatment with Early Initiation of Antiretroviral Therapy for HIV Co-Infected Patients in Lesotho 

      Satti, Hind Elkheir; McLaughlin, Megan M; Hedt-Gauthier, Bethany; Atwood, Sidney S.; Omotayo, David B.; Ntlamelle, Likhapha; Seung, Kwonjune Justin (Public Library of Science, 2012)
      Background: Although the importance of concurrent treatment for multidrug-resistant tuberculosis (MDR-TB) and HIV co-infection has been increasingly recognized, there have been few studies reporting outcomes of MDR-TB and ...