Now showing items 1-6 of 6

    • Bootstrapped Biocatalysis: Biofilm-Derived Materials as Reversibly Functionalizable Multienzyme Surfaces 

      Nussbaumer, Martin G.; Nguyen, Peter Q; Tay, Pei K. R.; Naydich, Alexander; Hysi, Erisa; Botyanszki, Zsofia; Joshi, Neel S. (Wiley-Blackwell, 2017)
      Cell-free biocatalysis systems offer many benefits for chemical manufacturing, but their widespread applicability is hindered by high costs associated with enzyme purification, modification, and immobilization on solid ...
    • Engineered catalytic biofilms: Site-specific enzyme immobilization onto E. coli curli nanofibers 

      Botyanszki, Zsofia; Tay, Pei Kun Richie Richie; Nguyen, Peter Q; Nussbaumer, Martin; Joshi, Neel S. (Wiley-Blackwell, 2015)
      Biocatalytic transformations generally rely on purified enzymes or whole cells to perform complex transformations that are used on industrial scale for chemical, drug, and biofuel synthesis, pesticide decontamination, and ...
    • Mechanical Reinforcement of Polymeric Fibers through Peptide Nanotube Incorporation 

      Rubin, Daniel James; Nia, Hadi T.; Desire, Thierry; Nguyen, Peter Q; Gevelber, Michael; Ortiz, Christine; Joshi, Neel S. (American Chemical Society (ACS), 2013)
      High aspect ratio nanotubular assemblies can be effective fillers in mechanically reinforced composite materials. However, most existing nanotubes used for structural purposes are limited in their range of mechanical, ...
    • Portable, On-Demand Biomolecular Manufacturing 

      Pardee, Keith; Slomovic, Shimyn; Nguyen, Peter Q; Lee, Jeong Wook; Donghia, Nina Marie; Burrill, Devin; Ferrante, Tom; McSorley, Fern R.; Furuta, Yoshikazu; Vernet, Andyna; Lewandowski, Michael P; Boddy, Christopher N.; Joshi, Neel S.; Collins, James J. (Elsevier BV, 2016)
      Synthetic biology uses living cells as molecular foundries for the biosynthesis of drugs, therapeutic proteins, and other commodities. However, the need for specialized equipment and refrigeration for production and ...
    • Programmable biofilm-based materials from engineered curli nanofibres 

      Nguyen, Peter Q; Botyanszki, Zsofia; Tay, Pei Kun Richie; Joshi, Neel S. (Nature Publishing Group, 2014)
      The significant role of biofilms in pathogenicity has spurred research into preventing their formation and promoting their disruption, resulting in overlooked opportunities to develop biofilms as a synthetic biological ...
    • A Synthetic Circuit for Mercury Bioremediation Using Self-Assembling Functional Amyloids 

      Tay, Pei Kun Richie Richie; Nguyen, Peter Q; Joshi, Neel S. (American Chemical Society (ACS), 2017)
      Synthetic biology approaches to bioremediation are a key sustainable strategy to leverage the self-replicating and programmable aspects of biology for environmental stewardship. The increasing spread of anthropogenic mercury ...