Browsing by Author "Bedoret, Denis"
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Changes in antigen-specific T cell number and function during oral desensitization in cow’s milk allergy enabled with omalizumab
Bedoret, Denis; Singh, A K; Shaw, V; Hoyte, E G; Hamilton, R; DeKruyff, Rosemarie H.; Schneider, Lynda C.; Nadeau, K C; Umetsu, Dale T. (2012)Food allergy is a major public health problem for which there is no effective treatment. We examined the immunological changes that occurred in a group of children with significant cow’s milk allergy undergoing a novel and ... -
RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance
Xiao, Yanping; Yu, Sanhong; Zhu, Baogong; Bedoret, Denis; Bu, Xia; Francisco, Loise M.; Hua, Ping; Duke-Cohan, Jonathan S.; Umetsu, Dale T.; Sharpe, Arlene H.; DeKruyff, Rosemarie H.; Freeman, Gordon J. (The Rockefeller University Press, 2014)We report that programmed death ligand 2 (PD-L2), a known ligand of PD-1, also binds to repulsive guidance molecule b (RGMb), which was originally identified in the nervous system as a co-receptor for bone morphogenetic ...