Now showing items 1-16 of 16

    • Assessment of cleaning to control lead dust in homes of children with moderate lead poisoning: treatment of lead-exposed children trial 

      Ettinger, Adrienne S; Bornschein, Robert L; Farfel, Mark; Campbell, Carla; Ragan, N Beth; Rhoads, George G; Brophy, Merrill; Wilkens, Sherry; Dockery, Douglas W. (National Institute of Environmental Health Sciences, 2002)
      In this article we describe the assessment and control of lead dust exposure in the Treatment of Lead-exposed Children (TLC) Trial, a clinical trial of the effects of oral chelation on developmental end points in urban ...
    • Association between Prenatal Lead Exposure and Blood Pressure in Children 

      Zhang, Aimin; Hu, Howard; Sánchez, Brisa N.; Ettinger, Adrienne S; Park, Sung Kyun; Cantonwine, David; Schnaas, Lourdes; Wright, Robert O.; Lamadrid-Figueroa, Hector; Tellez-Rojo, Martha Maria (National Institute of Environmental Health Sciences, 2012)
      Background: Lead exposure in adults is associated with hypertension. Altered prenatal nutrition is associated with subsequent risks of adult hypertension, but little is known about whether prenatal exposure to toxicants, ...
    • Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment 

      Henn, Birgit Claus; Schnaas, Lourdes; Lamadrid-Figueroa, Héctor; Hernández-Avila, Mauricio; Hu, Howard; Téllez-Rojo, Martha María; Ettinger, Adrienne S; Schwartz, Joel David; Amarasiriwardena, Chitra J.; Bellinger, David C.; Wright, Robert O. (National Institute of Environmental Health Sciences, 2011)
      Background: Most toxicologic studies focus on a single agent, although this does not reflect real-world scenarios in which humans are exposed to multiple chemicals. Objectives: We prospectively studied manganese–lead ...
    • Effect of breast milk lead on infant blood lead levels at 1 month of age 

      Ettinger, Adrienne S; Téllez-Rojo, Martha María; Amarasiriwardena, Chitra J.; Bellinger, David C.; Peterson, Karen E.; Schwartz, Joel David; Hu, Howard; Hernández-Avila, Mauricio (National Institue of Environmental Health Sciences, 2004)
      Nursing infants may be exposed to lead from breast milk, but relatively few data exist with which to evaluate and quantify this relationship. This route of exposure constitutes a potential infant hazard from mothers with ...
    • Effect of Calcium Supplementation on Blood Lead Levels in Pregnancy: A Randomized Placebo-Controlled Trial 

      Lamadrid-Figueroa, Héctor; Téllez-Rojo, Martha M.; Mercado-García, Adriana; Hu, Howard; Hernández-Avila, Mauricio; Ettinger, Adrienne S; Peterson, Karen E.; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2008)
      Background: Prenatal lead exposure is associated with deficits in fetal growth and neurodevelopment. Calcium supplementation may attenuate fetal exposure by inhibiting mobilization of maternal bone lead and/or intestinal ...
    • Fetal Lead Exposure at Each Stage of Pregnancy as a Predictor of Infant Mental Development 

      Hu, Howard; Téllez-Rojo, Martha María; Lamadrid-Figueroa, Héctor; Schnaas, Lourdes; Mercado-García, Adriana; Hernández-Avila, Mauricio; Bellinger, David C.; Smith, Donald; Ettinger, Adrienne S; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2006)
      Background: The impact of prenatal lead exposure on neurodevelopment remains unclear in terms of consistency, the trimester of greatest vulnerability, and the best method for estimating fetal lead exposure. Objective: We ...
    • HFE Gene Variants Modify the Association between Maternal Lead Burden and Infant Birthweight: A Prospective Birth Cohort Study in Mexico City, Mexico 

      Cantonwine, David; Hu, Howard; Téllez-Rojo, Martha Maria; Sánchez, Brisa N; Lamadrid-Figueroa, Héctor; Mercado-García, Adriana; Hernández-Avila, Mauricio; Ettinger, Adrienne S; Wright, Robert O. (BioMed Central, 2010)
      Background: Neonatal growth is a complex process involving genetic and environmental factors. Polymorphisms in the hemochromatosis (HFE) iron regulatory genes have been shown to modify transport and toxicity of lead which ...
    • Influence of Prenatal Lead Exposure on Genomic Methylation of Cord Blood DNA 

      Pilsner, J. Richard; Hu, Howard; Sánchez, Brisa N.; Cantonwine, David; Lazarus, Alicia; Lamadrid-Figueroa, Héctor; Mercado-García, Adriana; Téllez-Rojo, Martha Maria; Hernández-Avila, Mauricio; Ettinger, Adrienne S; Wright, Robert O. (National Institute of Environmental Health Sciences, 2009)
      Background: Fetal lead exposure is associated with adverse pregnancy outcomes and developmental and cognitive deficits; however, the mechanism(s) by which lead-induced toxicity occurs remains unknown. Epigenetic fetal ...
    • Lead Exposure and Behavior Among Young Children in Chennai, India 

      Roy, Ananya; Bellinger, David C.; Hu, Howard; Schwartz, Joel David; Ettinger, Adrienne S; Wright, Robert O.; Bouchard, Maryse; Palaniappan, Kavitha; Balakrishnan, Kalpana (National Institute of Environmental Health Sciences, 2009)
      Background: Lead exposure has long been associated with deficits in IQ among children. However, few studies have assessed the impact of lead on specific domains of behavior and cognition. Objective: We evaluated the ...
    • Levels of Lead in Breast Milk and Their Relation to Maternal Blood and Bone Lead Levels at One Month Postpartum. 

      Téllez-Rojo, Martha María; González-Cossío, Teresa; Aro, Antonio; Hu, Howard; Hernández-Avila, Mauricio; Ettinger, Adrienne S; Amarasiriwardena, Chitra J.; Peterson, Karen E. (National Institute of Environmental Health Sciences, 2004)
      Despite the many well-recognized benefits of breast-feeding for both mothers and infants, detectable levels of lead in breast milk have been documented in population studies of women with no current environmental or ...
    • Maternal arsenic exposure and impaired glucose tolerance during pregnancy 

      Ettinger, Adrienne S; Zota, Ami R.; Amarasiriwardena, Chitra J.; Hopkins, Marianne; Schwartz, Joel David; Hu, Howard; Wright, Robert O. (National Institute of Environmental Health Sciences, 2009)
      Background: Accumulating evidence has shown an increased risk of type 2 diabetes in general populations exposed to arsenic, but little is known about exposures during pregnancy and the association with gestational diabetes ...
    • A preliminary assessment of low level arsenic exposure and diabetes mellitus in Cyprus 

      Makris, Konstantinos C.; Christophi, Costas A.; Paisi, Martha; Ettinger, Adrienne S (BioMed Central, 2012)
      Background: A preliminary study was undertaken in a community of Cyprus where low-level arsenic (As) concentrations were recently detected in the groundwater that was chronically used to satisfy potable needs of the ...
    • Urinary Benzene Biomarkers and DNA Methylation in Bulgarian Petrochemical Workers: Study Findings and Comparison of Linear and Beta Regression Models 

      Seow, Wei Jie; Pesatori, Angela Cecilia; Dimont, Emmanuel; Farmer, Peter B.; Albetti, Benedetta; Ettinger, Adrienne S.; Bollati, Valentina; Bolognesi, Claudia; Roggieri, Paola; Panev, Teodor I.; Georgieva, Tzveta; Merlo, Domenico Franco; Bertazzi, Pier Alberto; Baccarelli, Andrea (Public Library of Science, 2012)
      Chronic occupational exposure to benzene is associated with an increased risk of hematological malignancies such as acute myeloid leukemia (AML), but the underlying mechanisms are still unclear. The main objective of this ...
    • Urinary Phthalate Metabolites in Relation to Preterm Birth in Mexico City 

      Meeker, John D.; Hu, Howard; Cantonwine, David E.; Lamadrid-Figueroa, Hector; Calafat, Antonia M.; Ettinger, Adrienne S; Hernandez-Avila, Mauricio; Loch-Caruso, Rita; Téllez-Rojo, Martha María (National Institute of Environmental Health Sciences, 2009)
      Background: Rates of preterm birth have been rising over the past several decades. Factors contributing to this trend remain largely unclear, and exposure to environmental contaminants may play a role. Objective: We ...
    • Using Nutrition for Intervention and Prevention Against Environmental Chemical Toxicity and Associated Diseases 

      Hennig, Bernhard; Ettinger, Adrienne S; Jandacek, Ronald J.; Koo, Sung; McClain, Craig David; Seifried, Harold; Silverstone, Allen; Watkins, Bruce; Suk, William A. (National Institute of Environmental Health Sciences, 2007)
      Background: Nutrition and lifestyle are well-defined modulators of chronic diseases. Poor dietary habits (such as high intake of processed foods rich in fat and low intake of fruits and vegetables), as well as a sedentary ...
    • Variants in iron metabolism genes predict higher blood lead levels in young children 

      Hopkins, Marianne; Ettinger, Adrienne S; Hernández-Avila, Mauricio; Schwartz, Joel David; Téllez-Rojo, Martha María; Lamadrid-Figueroa, Héctor; Bellinger, David C.; Hu, Howard; Wright, Robert O. (National Institute of Environmental Health Sciences, 2008)
      Background: Given the association between iron deficiency and lead absorption, we hypothesized that variants in iron metabolism genes would predict higher blood lead levels in young children. Objective: We examined the ...