Browsing by Author "Hua, Jing"
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Environmental conditioning in the control of macrophage thrombospondin-1 production
Fordham, Jezrom B.; Hua, Jing; Morwood, Sarah R.; Schewitz-Bowers, Lauren P.; Copland, David A.; Dick, Andrew D.; Nicholson, Lindsay B. (Nature Publishing Group, 2012)Thrombospondin-1 (TSP-1) is a multifunctional protein which is secreted into the extracellular matrix during inflammation, where it modulates numerous components of the immune infiltrate. Macrophages are a source of TSP-1, ... -
Resveratrol Inhibits Pathologic Retinal Neovascularization in Vldlr -/- Mice
Hua, Jing; Guerin, Karen I.; Chen, Jing; Michán, Shaday; Stahl, Andreas; Krah, Nathan M.; Seaward, Molly R.; Dennison, Roberta; Juan, Aimee M.; Hatton, Colman J.; Sapieha, Przemyslaw; Sinclair, David Andrew; Smith, Lois Elaine Hodgson (Association for Research in Vision and Ophthalmology (ARVO), 2011)PURPOSE: Macular telangiectasia (MacTel) is a vision-threatening retinal disease with unknown pathogenesis and no approved treatment. Very low-density lipoprotein receptor mutant mice (Vldlr(-/-)) exhibit critical features ... -
Wnt Signaling Mediates Pathological Vascular Growth in Proliferative Retinopathy Clinical Perspective
Chen, Jing; Stahl, Andreas; Krah, Nathan M.; Seaward, Molly R.; Dennison, Roberta; Sapieha, Przemyslaw; Hua, Jing; Hatton, Colman J.; Juan, Aimee M.; Aderman, Christopher; Willett, Keirnan L.; Guerin, Karen I.; Mammoto, Akiko; Campbell, Matthew; Smith, Lois Elaine Hodgson (Ovid Technologies (Wolters Kluwer Health), 2011)BACKGROUND: Ischemic proliferative retinopathy, characterized by pathological retinal neovascularization, is a major cause of blindness in working-age adults and children. Defining the molecular pathways distinguishing ...