Now showing items 1-5 of 5

    • Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy 

      Ji, Minbiao; Lewis, Spencer; Camelo-Piragua, Sandra; Ramkissoon, Shakti; Snuderl, Matija; Venneti, Sriram; Fisher-Hubbard, Amanda; Garrard, Mia; Fu, Dan; Wang, Anthony C.; Heth, Jason A.; Maher, Cormac O.; Sanai, Nader; Johnson, Timothy D.; Freudiger, Christian; Sagher, Oren; Xie, Xiaoliang Sunney; Orringer, Daniel A. (American Association for the Advancement of Science (AAAS), 2015)
      Differentiating tumor from normal brain is a major barrier to achieving optimal outcome in brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery are needed to improve surgical results. ...
    • Multicolor stimulated Raman scattering microscopy 

      Lu, Fake; Ji, Minbiao; Fu, Dan; Ni, Xiaohui; Freudiger, Christian Wilhelm; Holtom, Gary; Xie, Xiaoliang Sunney (Informa UK (Taylor & Francis), 2012)
      Stimulated Raman scattering (SRS) microscopy has opened up a wide range of biochemical imaging applications by probing a particular Raman-active molecule vibrational mode in the specimen. However, the original implementation ...
    • Multicolor Stimulated Raman Scattering Microscopy with a Rapidly Tunable Optical Parametric Oscillator 

      Kong, Lingjie; Ji, Minbiao; Holtom, Gary R.; Fu, Dan; Freudiger, Christian Wilhelm; Xie, Xiaoliang Sunney (Optical Society of America, 2013)
      Stimulated Raman scattering (SRS) microscopy allows label-free chemical imaging based on vibrational spectroscopy. Narrowband excitation with picosecond lasers creates the highest signal levels and enables imaging speeds ...
    • Multicolored Stain-Free Histopathology with Coherent Raman Imaging 

      Xie, Xiaoliang Sunney; Freudiger, Christian Wilhelm; Orringer, Daniel A.; Saar, Brian G.; Ji, Minbiao; Zeng, Qing; Ottoboni, Linda; Ying, Wei; Waeber, Christian; Sims, John R.; De Jager, Philip Lawrence; Sagher, Oren; Philbert, Martin A.; Xu, Xiaoyin; Kesari, Santosh; Young, Geoffrey; Pfannl, Rolf (Nature Publishing Group, 2012)
      Conventional histopathology with hematoxylin & eosin (H&E) has been the gold standard for histopathological diagnosis of a wide range of diseases. However, it is not performed in vivo and requires thin tissue sections ...
    • Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy 

      Ji, Minbiao; Orringer, Daniel A.; Freudiger, Christian Wilhelm; Ramkissoon, Shakti; Liu, Xiaohui; Lau, Darryl; Golby, Alexandra Jacqueline; Norton, Isaiah Hakim; Hayashi, Marika; Agar, Nathalie Marie Yvonne Rachel; Young, Geoffrey; Spino, Cathie; Santagata, Sandro; Camelo-Piragua, Sandra; Ligon, Keith Lloyd; Sagher, Oren; Xie, Xiaoliang Sunney (American Association for the Advancement of Science (AAAS), 2013)
      Surgery is an essential component in the treatment of brain tumors. However, delineating tumor from normal brain remains a major challenge. We describe the use of stimulated Raman scattering (SRS) microscopy for ...