Browsing by Author "Dockery, Douglas"
Now showing items 1-20 of 21
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3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) and mutagenic activity in Massachusetts drinking water.
Wright, J Michael; Schwartz, Joel David; Vartiainen, Terttu; Mäki-Paakkanen, Jorma; Altshul, Larisa M.; Harrington, Joseph J; Dockery, Douglas W. (2002)There is limited information on the prevalence of the potent mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in U.S. water supplies. We measured MX concentrations and mutagenic activity in tap water samples ... -
Assessment of cleaning to control lead dust in homes of children with moderate lead poisoning: treatment of lead-exposed children trial
Ettinger, Adrienne S; Bornschein, Robert L; Farfel, Mark; Campbell, Carla; Ragan, N Beth; Rhoads, George G; Brophy, Merrill; Wilkens, Sherry; Dockery, Douglas W. (National Institute of Environmental Health Sciences, 2002)In this article we describe the assessment and control of lead dust exposure in the Treatment of Lead-exposed Children (TLC) Trial, a clinical trial of the effects of oral chelation on developmental end points in urban ... -
Association of Short-term Ambient Air Pollution Concentrations and Ventricular Arrhythmias
Rich, David Q.; Schwartz, Joel; Mittleman, Murray A.; Link, Mark; Luttmann-Gibson, Heike; Catalano, Paul J.; Speizer, Frank E.; Dockery, Douglas (Oxford University Press (OUP), 2005-06-15)The authors evaluated the association between ventricular arrhythmias detected by implantable cardioverter defibrillators and ambient air pollution concentrations in the hours immediately before the arrhythmia. Patients ... -
Birth Outcomes in a Prospective Pregnancy-Birth Cohort Study of Environmental Risk Factors in Kuwait: The TRACER Study
Alseaidan, Mohammad M.S.; Al Wotayan, Rihab; Christophi, Costas A.; Al-Makhseed, Massouma; Abu Awad, Yara; Nassan, Feiby; Ahmed, Ayah; Abraham, Smitha; Boley, Robert Bruce; James-Todd, Tamarra; Wright, Rosalind; Dockery, Douglas William; Behbehani, Kazem (Wiley-Blackwell, 2016)Background—Rapid development and westernisation in Kuwait and other Gulf states have been accompanied by rising rates of obesity, diabetes, asthma, and other chronic conditions. Prenatal experiences and exposures may be ... -
Chronic Exposure to Fine Particles and Mortality: An Extended Follow-up of the Harvard Six Cities Study from 1974 to 2009
Lepeule, Johanna; Laden, Francine; Dockery, Douglas W.; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2012)Background: Epidemiologic studies have reported associations between fine particles (aerodynamic diameter ≤ 2.5 µm; PM:2.5) and mortality. However, concerns have been raised regarding the sensitivity of the results to model ... -
Countervailing effects of income, air pollution, smoking, and obesity on aging and life expectancy: population-based study of U.S. Counties
Allen, Ryan T.; Hales, Nicholas M.; Baccarelli, Andrea; Jerrett, Michael; Ezzati, Majid; Dockery, Douglas W.; Pope, C. Arden (BioMed Central, 2016)Background: Income, air pollution, obesity, and smoking are primary factors associated with human health and longevity in population-based studies. These four factors may have countervailing impacts on longevity. This ... -
Does Living Near a Superfund Site Contribute to Higher Polychlorinated Biphenyl (PCB) Exposure?
Tolbert, Paige E.; Choi, Anna L; Choi, Anna Lai; Levy, Jonathan Ian; Dockery, Douglas W.; Ryan, Louise Marie; Altshul, Larisa; Korrick, Susan Abigail (National Institute of Environmental Health Sciences, 2006)We assessed determinants of cord serum polychlorinated biphenyl (PCB) levels among 720 infants born between 1993 and 1998 to mothers living near a PCB-contaminated Superfund site in Massachusetts, measuring the sum of 51 ... -
Epidemiologic Evidence of Cardiovascular Effects of Particulate Air Pollution
Dockery, Douglas W. (National Institute of Environmental Health Sciences, 2001)In the past decade researchers have developed a body of epidemiologic evidence showing increased daily cardiovascular mortality and morbidity associated with acute exposures to particulate air pollution. Associations have ... -
Epidemiologic study design for investigating respiratory health effects of complex air pollution mixtures.
Dockery, Douglas W. (1993)Epidemiologic studies of the respiratory health effects of air pollution are intrinsically difficult because exposure is common, expected effects at concentrations found in developed countries are weak, random misclassification ... -
Feasibility of a large cohort study in sub-Saharan Africa assessed through a four-country study
Dalal, Shona; Holmes, Michelle D.; Laurence, Carien; Bajunirwe, Francis; Guwatudde, David; Njelekela, Marina; Adebamowo, Clement; Nankya-Mutyoba, Joan; Chiwanga, Faraja S.; Volmink, Jimmy; Ajayi, Ikeoluwapo; Kalyesubula, Robert; Reid, Todd G.; Dockery, Douglas; Hemenway, David; Adami, Hans-Olov (Co-Action Publishing, 2015)Background: Large prospective epidemiologic studies are vital in determining disease etiology and forming national health policy. Yet, such studies do not exist in sub-Saharan Africa (SSA) notwithstanding the growing burden ... -
Fungus Spores, Air Pollutants, and Other Determinants of Peak Expiratory Flow Rate in Children
Neas, L. M.; Burge, H.; Koutrakis, p.; Speizer, F. E.; Dockery, Douglas (Oxford University Press (OUP), 1996-04-15)The impact of summertime haze episodes on daily variations in symptoms and peak expiratory flow rates (PEFRs) was examined in a study of 108 children living in State College, Pennsylvania, during the summer of 1991. Twice ... -
Increased Particulate Air Pollution and the Triggering of Myocardial Infarction
Peters, Annette; Dockery, Douglas; Muller, James E.; Mittleman, Murray A. (Ovid Technologies (Wolters Kluwer Health), 2001-06-12)Background - Elevated concentrations of ambient particulate air pollution have been associated with increased hospital admissions for cardiovascular disease. Whether high concentrations of ambient particles can trigger the ... -
Increased Risk of Paroxysmal Atrial Fibrillation Episodes Associated with Acute Increases in Ambient Air Pollution
Rich, David Q.; Mittleman, Murray A.; Link, Mark S.; Schwartz, Joel David; Luttmann-Gibson, Heike; Catalano, Paul J.; Speizer, Frank Erwin; Gold, Diane R.; Dockery, Douglas W. (National Institute of Environmental Health Sciences, 2006)Objectives: We reported previously that 24-hr moving average ambient air pollution concentrations were positively associated with ventricular arrhythmias detected by implantable cardioverter defibrillators (ICDs). ICDs ... -
Lung Cancer in Railroad Workers Exposed to Diesel Exhaust
Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Rosner, Bernard Alfred; Smith, Thomas J.; Dockery, Douglas W.; Speizer, Frank Erwin (National Institue of Environmental Health Sciences, 2004)Diesel exhaust has been suspected to be a lung carcinogen. The assessment of this lung cancer risk has been limited by lack of studies of exposed workers followed for many years. In this study, we assessed lung cancer ... -
Maternal, Behavioral, and Environmental Risk Factors for Gestational Diabetes and Preterm Birth Among Pregnant Women
Alseaidan, Mohammad (2016-04-25)Background: Lifestyle changed in Kuwait with the rapid development and economic expansion and the Americanization of the Kuwaiti market. Fast food and sedentary lifestyle became very prevalent. Environmental exposures such ... -
Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study
Moreno-Macías, Hortensia; Dockery, Douglas W.; Schwartz, Joel David; Gold, Diane R.; Laird, Nan M.; Sienra-Monge, Juan J; Del Río-Navarro, Blanca E; Ramírez-Aguilar, Matiana; Barraza-Villarreal, Albino; Li, Huiling; London, Stephanie J; Romieu, Isabelle (BioMed Central, 2013)Background: We previously reported that asthmatic children with GSTM1 null genotype may be more susceptible to the acute effect of ozone on the small airways and might benefit from antioxidant supplementation. This study ... -
Particulate Air Pollution, Exceptional Aging, and Rates of Centenarians: A Nationwide Analysis of the United States, 1980–2010
Baccarelli, Andrea A.; Hales, Nick; Burnett, Richard T.; Jerrett, Michael; Mix, Carter; Dockery, Douglas W.; Pope, C. Arden (National Institute of Environmental Health Sciences, 2016)Background: Exceptional aging, defined as reaching age 85 years, shows geographic inequalities that may depend on local environmental conditions. Links between particulate pollution—a well-recognized environmental risk ... -
Pulmonary Toxicity in Hamsters of Smoke Particles from Kuwaiti Oil Fires.
Brain, Joseph David; Long, N. C.; Wolfthal, S F; Dumyahn, T; Dockery, Douglas W. (National Institute of Environmental Health Sciences, 1998)The Kuwaiti oil wells set on fire by retreating Iraqi troops at the end of the Persian Gulf War released complex particles, inorganic and organic gases, and hydrocarbons into the atmosphere, damaging the environment where ... -
Traffic-related exposures and biomarkers of systemic inflammation, endothelial activation and oxidative stress: a panel study in the US trucking industry
Neophytou, Andreas M; Hart, Jaime E; Cavallari, Jennifer M; Smith, Thomas J; Dockery, Douglas W; Coull, Brent A; Garshick, Eric; Laden, Francine (BioMed Central, 2013)Background: Experimental evidence suggests that inhaled particles from vehicle exhaust have systemic effects on inflammation, endothelial activation and oxidative stress. In the present study we assess the relationships ... -
Urban–rural and geographic differences in overweight and obesity in four sub-Saharan African adult populations: a multi-country cross-sectional study
Ajayi, IkeOluwapo O.; Adebamowo, Clement; Adami, Hans-Olov; Dalal, Shona; Diamond, Megan B.; Bajunirwe, Francis; Guwatudde, David; Njelekela, Marina; Nankya-Mutyoba, Joan; Chiwanga, Faraja S.; Volmink, Jimmy; Kalyesubula, Robert; Laurence, Carien; Reid, Todd G.; Dockery, Douglas; Hemenway, David; Spiegelman, Donna; Holmes, Michelle D. (BioMed Central, 2016)Background: Overweight and obesity are on the rise in developing countries including sub-Saharan Africa. We undertook a four-country survey to show the collective burden of these health conditions as they occur currently ...