Now showing items 1-2 of 2

    • Adapting Quantitative Protein and Phosphorylation Analyses to a Proteome-Wide Scale 

      Grady, Joshua Terrence Wilson (2013-09-30)
      Liquid chromatography coupled tandem mass spectrometry (LC-MS/MS) has become the preferred method for large-scale peptide and phosphopeptide identification and quantification. The dominance of LC-MS/MS is the result of ...
    • C. elegans SIRT6/7 Homolog SIR-2.4 Promotes DAF-16 Relocalization and Function during Stress 

      Chiang, Wei-Chung; Tishkoff, Daniel X.; Yang, Bo; Grady, Joshua Terrence Wilson; Yu, Xiaokun; Mazer, Travis; Eckersdorff, Mark; Gygi, Steven P.; Lombard, David B.; Hsu, Ao-Lin (Public Library of Science, 2012)
      FoxO transcription factors and sirtuin family deacetylases regulate diverse biological processes, including stress responses and longevity. Here we show that the Caenorhabditis elegans sirtuin SIR-2.4—homolog of mammalian ...