Browsing by Author "Chandraker, Anil"

Now showing items 1-7 of 7

    • Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection 

      Lin, Ming V.; Sise, Meghan E.; Pavlakis, Martha; Amundsen, Beth M.; Chute, Donald; Rutherford, Anna E.; Chung, Raymond T.; Curry, Michael P.; Hanifi, Jasmine M.; Gabardi, Steve; Chandraker, Anil; Heher, Eliot C.; Elias, Nahel; Riella, Leonardo V. (Public Library of Science, 2016)
      The prevalence of Hepatitis C Virus (HCV) infection is significantly higher in patients with end-stage renal disease compared to the general population and poses important clinical challenges in patients who undergo kidney ...

    • Immunologic monitoring in kidney transplant recipients 

      Townamchai, Natavudh; Safa, Kassem; Chandraker, Anil (Elsevier, 2013)
      Transplant biopsy has always been the gold standard for assessing the immune response to a kidney allograft (Chandraker A: Diagnostic techniques in the work-up of renal allograft dysfunction—an update. Curr Opin Nephrol ...

    • The Limits of Linked Suppression for Regulatory T Cells 

      Ito, Toshiro; Yamada, Akira; Batal, Ibrahim; Yeung, Melissa Y.; McGrath, Martina M.; Sayegh, Mohamed H.; Chandraker, Anil; Ueno, Takuya (Frontiers Media S.A., 2016)
      Background: We have previously found that CD4+CD25+ regulatory T cells (Tregs) can adoptively transfer tolerance after its induction with costimulatory blockade in a mouse model of murine cardiac allograft transplantation. ...

    • Live Images of Donor Dendritic Cells Trafficking via CX3CR1 Pathway 

      Ueno, Takuya; Kim, Pilhan; McGrath, Martina M.; Yeung, Melissa Y.; Shimizu, Tetsunosuke; Jung, Keehoon; Sayegh, Mohamed H.; Chandraker, Anil K.; Abdi, Reza; Yun, Seok H. (Frontiers Media S.A., 2016)
      Background: A number of studies have demonstrated the role of CX3CR1 in regulating the migration of monocytes into peripheral tissue and their transformation into dendritic cell (DC). No data are yet available on the ...

    • Metabolomic Profiling in Individuals with a Failing Kidney Allograft 

      Bassi, Roberto; Niewczas, Monika A.; Biancone, Luigi; Bussolino, Stefania; Merugumala, Sai; Tezza, Sara; D’Addio, Francesca; Ben Nasr, Moufida; Valderrama-Vasquez, Alessandro; Usuelli, Vera; De Zan, Valentina; El Essawy, Basset; Venturini, Massimo; Secchi, Antonio; De Cobelli, Francesco; Lin, Alexander; Chandraker, Anil; Fiorina, Paolo (Public Library of Science, 2017)
      Background: Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. Methods: To explore metabolomic abnormalities in individuals with a failing kidney allograft, we analyzed by ...

    • TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer 

      GRIMMIG, TANJA; MATTHES, NIELS; HOELAND, KATHARINA; TRIPATHI, SUDIPTA; CHANDRAKER, ANIL; GRIMM, MARTIN; MOENCH, ROMANA; MOLL, EVA-MARIA; FRIESS, HELMUT; TSAUR, IGOR; BLAHETA, ROMAN A.; GERMER, CRISTOPH T.; WAAGA-GASSER, ANA MARIA; GASSER, MARTIN (D.A. Spandidos, 2015)
      Chronic inflammation as an important epigenetic and environmental factor for putative tumorigenesis and tumor progression may be associated with specific activation of Toll-like receptors (TLR). Recently, carcinogenesis ...

    • Toll Like Receptor 2, 4, and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer 

      Grimmig, Tanja; Moench, Romana; Kreckel, Jennifer; Haack, Stephanie; Rueckert, Felix; Rehder, Roberta; Tripathi, Sudipta; Ribas, Carmen; Chandraker, Anil; Germer, Christoph T.; Gasser, Martin; Waaga-Gasser, Ana Maria (MDPI, 2016)
      Toll like receptor (TLR) signaling has been suggested to play an important role in the inflammatory microenvironment of solid tumors and through this inflammation-mediated tumor growth. Here, we studied the role of tumor ...