Browsing by Author "Tsurumi, Amy"

Now showing items 1-3 of 3

    • Prediction of Multiple Infections After Severe Burn Trauma 

      Yan, Shuangchun; Tsurumi, Amy; Que, Yok-Ai; Ryan, Colleen M.; Bandyopadhaya, Arunava; Morgan, Alexander A.; Flaherty, Patrick J.; Tompkins, Ronald Gary; Rahme, Laurence G. (Ovid Technologies (Wolters Kluwer Health), 2015)
      OBJECTIVE: To develop predictive models for early triage of burn patients based on hypersusceptibility to repeated infections. BACKGROUND: Infection remains a major cause of mortality and morbidity after severe trauma, ...

    • A Quorum Sensing Small Volatile Molecule Promotes Antibiotic Tolerance in Bacteria 

      Que, Yok-Ai; Hazan, Ronen; Strobel, Benjamin; Maura, Damien; He, Jianxin; Kesarwani, Meenu; Panopoulos, Panagiotis; Tsurumi, Amy; Giddey, Marlyse; Wilhelmy, Julie; Mindrinos, Michael N.; Rahme, Laurence G. (Public Library of Science, 2013)
      Bacteria can be refractory to antibiotics due to a sub-population of dormant cells, called persisters that are highly tolerant to antibiotic exposure. The low frequency and transience of the antibiotic tolerant “persister” ...

    • TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections 

      Tsurumi, Amy; Que, Yok-Ai; Ryan, Colleen M.; Tompkins, Ronald G.; Rahme, Laurence G. (Frontiers Media S.A., 2016)
      Severe burn injury renders patients susceptible to multiple infection episodes; however, identifying specific patient groups at high risk remains challenging. Burn-induced inflammatory response dramatically modifies the ...