Browsing by Author "Coull, Brent"
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Acute and Chronic Effects of Particles on Hospital Admissions in New England
Coull, Brent Andrew; Zanobetti, Antonella; Koutrakis, Petros; Schwartz, Joel David (Public Library of Science, 2012)Background: Many studies have reported significant associations between exposure to \(PM_{2.5}\) and hospital admissions, but all have focused on the effects of short-term exposure. In addition all these studies have relied ... -
Air Pollution and ST-Segment Depression in Elderly Subjects
MacCallum, Gail; Canner, Marina J.; Gold, Diane R.; Litonjua, Augusto Ampil; Zanobetti, Antonella; Coull, Brent Andrew; Schwartz, Joel David; Verrier, Richard Leonard; Nearing, Bruce David; Suh MacIntosh, Helen H.; Stone, Peter Howard (National Institue of Environmental Health Sciences, 2005)Increased levels of daily ambient particle pollution have been associated with increased risk of cardiovascular morbidity. Black carbon (BC) is a measure of the traffic-related component of particles. We investigated ... -
Ambient Air Pollution and Depressive Symptoms in Older Adults: Results from the MOBILIZE Boston Study
Wang, Yi; Eliot, Melissa N.; Koutrakis, Petros; Gryparis, Alexandros; Schwartz, Joel D.; Coull, Brent A.; Mittleman, Murray A.; Milberg, William P.; Lipsitz, Lewis A.; Wellenius, Gregory A. (NLM-Export, 2014)Background: Exposure to ambient air pollution, particularly from traffic, has been associated with adverse cognitive outcomes, but the association with depressive symptoms remains unclear. Objectives: We investigated the ... -
Ambient air pollution, lung function, and airway responsiveness in asthmatic children
Ierodiakonou, Despo; Zanobetti, Antonella; Coull, Brent Andrew; Melly, Steven John; Postma, Dirkje S.; Boezen, H. Marike; Vonk, Judith M.; Williams, Paul V.; Shapiro, Gail G.; McKone, Edward F.; Hallstrand, Teal S.; Koenig, Jane Q.; Schildcrout, Jonathan S.; Lumley, Thomas; Fuhlbrigge, Anne Louise; Koutrakis, Petros; Schwartz, Joel David; Weiss, Scott Tillman; Gold, Diane R. (Elsevier BV, 2016)Background: Although ambient air pollution has been linked to reduced lung function in healthy children, longitudinal analyses of pollution effects in asthma are lacking. Objective: To investigate pollution effects in ... -
Ambient and Microenvironmental Particles and Exhaled Nitric Oxide Before and After a Group Bus Trip
Adar, Sara Dubowsky; Adamkiewicz, Gary; Gold, Diane R.; Schwartz, Joel David; Coull, Brent Andrew; Suh MacIntosh, Helen H. (National Institute of Environmental Health Sciences, 2007)Objectives: Airborne particles have been linked to pulmonary oxidative stress and inflammation. Because these effects may be particularly great for traffic-related particles, we examined associations between particle ... -
Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals
Rodosthenous, Rodosthenis S.; Coull, Brent A.; Lu, Quan; Vokonas, Pantel S.; Schwartz, Joel D.; Baccarelli, Andrea A. (BioMed Central, 2016)Background: Air pollution from particulate matter (PM) has been linked to cardiovascular morbidity and mortality; however the underlying biological mechanisms remain to be uncovered. Gene regulation by microRNAs (miRNAs) ... -
Annual Ambient Black Carbon Associated with Shorter Telomeres in Elderly Men: Veterans Affairs Normative Aging Study
Hoxha, Mirjam; Dioni, Laura; McCracken, John Patrick; Baccarelli, Andrea; Melly, Steven John; Coull, Brent Andrew; Suh MacIntosh, Helen H.; Vokonas, Pantel S; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2010)Background: Telomere length reflects biological age and is inversely associated with risk of cardiovascular disease (CVD). Ambient air pollution is associated with CVD, but its effect on telomere length is unknown. Objective: ... -
Associations between air pollution and perceived stress: the Veterans Administration Normative Aging Study
Mehta, Amar J; Kubzansky, Laura D; Coull, Brent A; Kloog, Itai; Koutrakis, Petros; Sparrow, David; Spiro, Avron; Vokonas, Pantel; Schwartz, Joel (BioMed Central, 2015)Background: There is mixed evidence suggesting that air pollution may be associated with increased risk of developing psychiatric disorders. We aimed to investigate the association between air pollution and non-specific ... -
Associations between Changes in City and Address Specific Temperature and QT Interval - The VA Normative Aging Study
Mehta, Amar J.; Kloog, Itai; Zanobetti, Antonella; Coull, Brent A.; Sparrow, David; Vokonas, Pantel; Schwartz, Joel (Public Library of Science, 2014)Background: The underlying mechanisms of the association between ambient temperature and cardiovascular morbidity and mortality are not well understood, particularly for daily temperature variability. We evaluated if daily ... -
Associations between Long-Term Exposure to Chemical Constituents of Fine Particulate Matter (PM2.5) and Mortality in Medicare Enrollees in the Eastern United States
Chung, Yeonseung; Dominici, Francesca; Wang, Yun; Coull, Brent A.; Bell, Michelle L. (NLM-Export, 2015)Background: Several epidemiological studies have reported that long-term exposure to fine particulate matter (PM2.5) is associated with higher mortality. Evidence regarding contributions of PM2.5 constituents is inconclusive. ... -
Associations between Prenatal Exposure to Black Carbon and Memory Domains in Urban Children: Modification by Sex and Prenatal Stress
Cowell, Whitney J.; Bellinger, David C.; Coull, Brent A.; Gennings, Chris; Wright, Robert O.; Wright, Rosalind J. (Public Library of Science, 2015)Background: Whether fetal neurodevelopment is disrupted by traffic-related air pollution is uncertain. Animal studies suggest that chemical and non-chemical stressors interact to impact neurodevelopment, and that this ... -
Associations between Traffic-Related Black Carbon Exposure and Attention in a Prospective Birth Cohort of Urban Children
Chiu, Yueh-Hsiu Mathilda; Bellinger, David C.; Coull, Brent A.; Anderson, Shawn; Barber, Rachel; Wright, Robert O.; Wright, Rosalind J. (National Institute of Environmental Health Sciences, 2013)Background: Ambient air pollution may have neurotoxic effects in children. Data examining associations between traffic-related air pollution and attention domains remain sparse. Objectives: We examined associations between ... -
Baseline Repeated Measures from Controlled Human Exposure Studies: Associations between Ambient Air Pollution Exposure and the Systemic Inflammatory Biomarkers IL-6 and Fibrinogen
Thompson, Aaron M.S.; Zanobetti, Antonella; Silverman, Frances; Schwartz, Joel David; Coull, Brent Andrew; Urch, Bruce; Speck, Mary; Brook, Jeffrey R.; Manno, Michael; Gold, Diane R. (National Institute of Environmental Health Sciences, 2009)Introduction: Systemic inflammation may be one of the mechanisms mediating the association between ambient air pollution and cardiovascular morbidity and mortality. Interleukin-6 (IL-6) and fibrinogen are biomarkers of ... -
Beyond the Mean: Quantile Regression to Explore the Association of Air Pollution with Gene-Specific Methylation in the Normative Aging Study
Bind, Marie-Abele C.; Coull, Brent A.; Peters, Annette; Baccarelli, Andrea A.; Tarantini, Letizia; Cantone, Laura; Vokonas, Pantel S.; Koutrakis, Petros; Schwartz, Joel D. (NLM-Export, 2015)Background: Air pollution has been related to mean changes in outcomes, including DNA methylation. However, mean regression analyses may not capture associations that occur primarily in the tails of the outcome distribution. ... -
Brachial Artery Responses to Ambient Pollution, Temperature, and Humidity in People with Type 2 Diabetes: A Repeated-Measures Study
Zanobetti, Antonella; Luttmann-Gibson, Heike; Horton, Edward S.; Cohen, Allison; Coull, Brent A.; Hoffmann, Barbara; Schwartz, Joel D.; Mittleman, Murray A.; Li, Yongsheng; Stone, Peter H.; de Souza, Celine; Lamparello, Brooke; Koutrakis, Petros; Gold, Diane R. (National Institute of Environmental Health Sciences, 2014)Background: Extreme weather and air pollution are associated with increased cardiovascular risk in people with diabetes. Objectives: In a population with diabetes, we conducted a novel assessment of vascular brachial artery ... -
Capture-recapture Estimation for Conflict Data and Hierarchical Models for Program Impact Evaluation
Mitchell, Shira Arkin (2014-06-06)A relatively recent increase in the popularity of evidence-based activism has created a higher demand for statisticians to work on human rights and economic development projects. The statistical challenges of revealing ... -
Cardiovascular Inflammation in Healthy Women: Multilevel Associations with State-Level Prosperity, Productivity and Income Inequality
Clark, Cheryl; Ridker, Paul M.; Ommerborn, Mark J; Huisingh, Carrie E; Coull, Brent Andrew; Buring, Julie Elizabeth; Berkman, Lisa Faye (BioMed Central, 2012)Background: Cardiovascular inflammation is a key contributor to the development of atherosclerosis and the prediction of cardiovascular events among healthy women. An emerging literature suggests biomarkers of inflammation ... -
A Case–Control Analysis of Exposure to Traffic and Acute Myocardial Infarction
Tonne, Cathryn; Melly, Steven John; Mittleman, Murray A.; Coull, Brent Andrew; Goldberg, Robert; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2006)Background: Long-term exposure to particulate air pollution has been associated with an increased risk of dying from cardiopulmonary and ischemic heart disease, yet few studies have evaluated cardiovascular end points other ... -
Concentrated Ambient Particles Alter Myocardial Blood Flow During Acute Ischemia in Conscious Canines
Bartoli, Carlo R.; Wellenius, Gregory A.; Coull, Brent Andrew; Akiyama, Ichiro; Diaz, Edgar; Lawrence, Joy E.; Okabe, Kazunori; Verrier, Richard Leonard; Godleski, John Joseph (National Institute of Environmental Health Sciences, 2008)Background: Experimental and observational studies have demonstrated that short-term exposure to ambient particulate matter (PM) exacerbates myocardial ischemia. Objectives: We conducted this study to investigate the effects ... -
Contribution of socioeconomic factors to the variation in body-mass index in 58 low-income and middle-income countries: an econometric analysis of multilevel data
Kim, Rockli; Kawachi, Ichiro; Coull, Brent Andrew; Subramanian, S.V. Venkata (Elsevier BV, 2018)Background Most epidemiological studies have not simultaneously quantified variance in health within and between populations. We aimed to estimate the extent to which basic socioeconomic factors contribute to variation ...