Browsing by Author "Bosl, William"
Now showing items 1-4 of 4
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EEG complexity as a biomarker for autism spectrum disorder risk
Bosl, William; Tierney, Adrienne; Tager-Flusberg, Helen; Nelson, Charles A. (Springer Science + Business Media, 2011)Background: Complex neurodevelopmental disorders may be characterized by subtle brain function signatures early in life before behavioral symptoms are apparent. Such endophenotypes may be measurable biomarkers for later ... -
The Role of Noise and Positive Feedback in the Onset of Autosomal Dominant Diseases
Bosl, William; Li, Rong (BioMed Central, 2010)Background: Autosomal dominant (AD) diseases result when a single mutant or non-functioning gene is present on an autosomal chromosome. These diseases often do not emerge at birth. There are presently two prevailing theories ... -
Rule-Based Cell Systems Model of Aging using Feedback Loop Motifs Mediated by Stress Responses
Kriete, Andres; Bosl, William; Booker, Glenn (Public Library of Science, 2010)Investigating the complex systems dynamics of the aging process requires integration of a broad range of cellular processes describing damage and functional decline co-existing with adaptive and protective regulatory ... -
Systems Biology by the Rules: Hybrid Intelligent Systems for Pathway Modeling and Discovery
Bosl, William (BioMed Central, 2007)Background: Expert knowledge in journal articles is an important source of data for reconstructing biological pathways and creating new hypotheses. An important need for medical research is to integrate this data with high ...