Now showing items 1-6 of 6

    • Evidence-based decision support for pediatric rheumatology reduces diagnostic errors 

      Segal, Michael M.; Athreya, Balu; Son, Mary Beth F.; Tirosh, Irit; Hausmann, Jonathan S.; Ang, Elizabeth Y. N.; Zurakowski, David; Feldman, Lynn K.; Sundel, Robert P. (BioMed Central, 2016)
      Background: The number of trained specialists world-wide is insufficient to serve all children with pediatric rheumatologic disorders, even in the countries with robust medical resources. We evaluated the potential of ...
    • Gene-Expression Patterns Reveal Underlying Biological Processes in Kawasaki Disease 

      Popper, Stephen J; Shimizu, Chisato; Shike, Hiroko; Kanegaye, John T; Newburger, Jane Wimpfheimer; Sundel, Robert Picard; Brown, Patrick O; Burns, Jane C.; Relman, David A (BioMed Central, 2007)
      Background: Kawasaki disease (KD) is an acute self-limited vasculitis and the leading cause of acquired heart disease in children in developed countries. No etiologic agent(s) has been identified, and the processes that ...
    • Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study 

      Lo, Mindy S; Zurakowski, David; Son, Mary Beth F; Sundel, Robert P (BioMed Central, 2013)
      Background: The significance of hypergammaglobulinemia as a marker of immune activation is unknown, as a differential diagnosis for hypergammaglobulinemia in children has not been adequately established. The goal of this ...
    • Idiopathic Pericarditis and Pericardial Effusion in Children: Contemporary Epidemiology and Management 

      Shakti, Divya; Hehn, Rebecca; Gauvreau, Kimberly; Sundel, Robert P.; Newburger, Jane W. (Blackwell Publishing Ltd, 2014)
      Background: Multicenter studies on idiopathic or viral pericarditis and pericardial effusion (PPE) have not been reported in children. Colchicine use for PPE in adults is supported. We explored epidemiology and management ...
    • Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study 

      Cornelissen, Laura; Donado, Carolina; Kim, Joseph; Chiel, Laura; Zurakowski, David; Logan, Deirdre E; Meier, Petra; Sethna, Navil F; Blankenburg, Markus; Zernikow, Boris; Sundel, Robert P; Berde, Charles B (BioMed Central, 2014)
      Background: Juvenile Idiopathic Arthritis (JIA) is the most common cause of non-infectious joint inflammation in children. Synovial inflammation results in pain, swelling and stiffness. Animal and adult human studies ...
    • Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease 

      Kentsis, Alex; Shulman, Andrew Ira; Ahmed, Saima; Brennan, Eileen; Monuteaux, Michael C; Lee, Young-Ho; Lipsett, Susan Catherine; Paulo, Joao A; Dedeoglu, Fatma; Fuhlbrigge, Robert Conrad; Bachur, Richard Gary; Bradwin, Gary; Arditi, Moshe; Sundel, Robert Picard; Newburger, Jane Wimpfheimer; Steen, Hanno; Kim, Susan (WILEY-VCH Verlag, 2013)
      Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. Absence of definitive diagnostic markers limits the accuracy of clinical evaluations of suspected KD with significant increases in morbidity. In turn, ...