Now showing items 1-2 of 2

    • High-throughput approaches to discover novel immunomodulatory agents for cancer 

      McMillin, Douglas William; Mitsiades, Constantine S (Landes Bioscience, 2012)
      The clinical success of immunomodulatory thalidomide derivatives has renewed the general interest in immunomodulatory anticancer compounds and prompted us to develop a high-throughput system to quantify immune effector-cell ...
    • Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ 

      Reagan, Michaela Ruth; Seib, F. Philipp; McMillin, Douglas William; Sage, Elizabeth K.; Mitsiades, Constantine S.; Janes, Sam M.; Ghobrial, Irene; Kaplan, David L. (Korean Breast Cancer Society, 2012)
      Purpose Tumor-specific delivery of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), an apoptosis-inducing peptide, at effective doses remains challenging. Herein we demonstrate the utility of a scaffold-based ...