Now showing items 1-3 of 3

    • Accurate Whole-Genome Sequencing and Haplotyping from 10 to 20 Human Cells 

      Peters, Brock A.; Kermani, Bahram G.; Sparks, Andrew B.; Alferov, Oleg; Hong, Peter; Alexeev, Andrei; Jiang, Yuan; Dahl, Fredrik; Tang, Y. Tom; Haas, Juergen; Robasky, Kimberly J.; Lee, Je-Hyuk; Peterson, Joseph E.; Perazich, Helena; Yeung, George; Liu, Jia; Chen, Linsu; Kennemer, Michael I.; Pothuraju, Kaliprasad; Konvicka, Karel; Tsoupko-Sitnikov, Mike; Pant, Krishna P.; Ebert, Jessica C.; Nilsen, Geoffrey B.; Baccash, Jonathan; Halpern, Aaron L.; Church, George McDonald; Drmanac, Radoje; Zaranek, Alexander Wait; Ball, Madeleine Price (Nature Publishing Group, 2012)
      Recent advances in whole genome sequencing have brought the vision of personal genomics and genomic medicine closer to reality. However, current methods lack clinical accuracy and the ability to describe the context ...
    • A Survey of Genomic Traces Reveals a Common Sequencing Error, RNA Editing, and DNA Editing 

      Zaranek, Alexander Wait; Levanon, Erez Y.; Zecharia, Tomer; Clegg, Tom; Church, George McDonald (Public Library of Science, 2010)
      While it is widely held that an organism's genomic information should remain constant, several protein families are known to modify it. Members of the AID/APOBEC protein family can deaminate DNA. Similarly, members of the ...
    • Swift: Primary Data Analysis for the Illumina Solexa Sequencing Platform 

      Whiteford, Nava; Skelly, Tom; Curtis, Christina; Ritchie, Matt E.; Löhr, Andrea; Zaranek, Alexander Wait; Abnizova, Irina; Brown, Clive (Oxford University Press, 2009)
      Motivation: Primary data analysis methods are of critical importance in second generation DNA sequencing. Improved methods have the potential to increase yield and reduce the error rates. Openly documented analysis tools ...